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A Multi-center, Double-Masked, Parallel Group, Placebo-Controlled Study to Assess the Efficacy
 and Safety of Voclosporin as Therapy in Subjects with Active Non-Infectious Uveitis Involving the
 Intermediate and/or Posterior Segments of the Eye

The primary objective of this study is to assess the safety and efficacy of voclosporin as therapy in subjects with active noninfectious uveitis involving the intermediate and/or posterior segments of the eye (i.e., anterior + intermediate-,…

The retro-orbital fibrobast: a key player in Graves* opthalmopathy and a target for therapy.

Development, optimization and implementation of retro-orbital fibroblast cultures in our laboratory.

A Multicenter Study of the Efficacy and Safety of the Human Anti-TNF Monoclonal Antibody Adalimumab as Maintenance Therapy in Subjects Requiring High Dose Corticosteroids for Active Non infectious Intermediate-, Posterior-, or Pan-uveitis

The objective of this study is to evaluate the efficacy and safety of adalimumab 80 mg loading dose followed by 40 mg dose given every other week (eow) subcutaneously (SC) starting at Week 1 compared with placebo as maintenance therapy in subjects…

A Multicenter Study of the Efficacy and Safety of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects with Inactive Non-infectious Intermediate-, Posterior-, or Pan-uveitis

The objective of this study is to evaluate the efficacy and safety of adalimumab 80 mg loading dose followed by 40 mg dose given every other week (eow) subcutaneously (SC) starting at Week 1 compared with placebo in subjects with inactive non-…

Determination of protein profiles in vitreous of eyes with endophthalmitis with Surface Enhanced Laser desorption/ ionization time-of-flight (SELDI-tof) technology.

To evaluate the usefulness of SELDI-tof (surface enhanced laser desorption/ ionisation-technology) technology in determination of disease-specific protein profiles of bacteria in vitreous of patients with endophthalmitis after cataract surgery.…

Effects of post-operative topical steroid versus intraoperative subconjunctival steroid injection and postoperative miotic on intraocular inflammation following cataract extraction.

Primary Objective: Comparison of incidence of post-cataract extraction ocular inflammation with subconjunctival steroid injection versus traditional eye drops.Secondary Objective: Evaluation of usefulness of physostigmine following cataract surgery.

Mycophenolate sodium (Myfortic) in the Treatment of Uveitis: a Pilot Study.

This study is designed to demonstrate equal therapeutic effect of Myfortic® as compared to MMF in this patient group, thus improving therapeutic efficacy.

Contributions to diagnosis and management of dry eye diseases: a systematic and stepwise approach.

The major goal of this study is to develop a systematic and stepwise approach for dry eyes. First, it will be evaluated whether Tes glasses are a diagnostic tool for dry eye diseases. Second, it will be evaluated or it can make a distinction between…

The pathogenesis and prognostic factors of scleritis

The primary goal of this study is to identify the presence and possible pathogenic role of auto-antibodies in scleritis patients. Secondary goals are to evaluate the presence and role of matrix metalloproteinases (MMPs) in scleritis and its…

Pathogenic role of virus-specific T-cells in corneas of patients with herpetic stromal keratitis (HSKPATH)

Elucidation of the pathogenic role of cornea-infiltrating HSV-specific T-cells in HSK patients.

Clinical implementation of an uveitis prediction model

To study the effect of the availability of a predictive uveitis model in the clinical setting on the 1 year visual outcome of patients.