45 results
Donor-specific antibodies form a significant barrier in transplantation of highly pre-sensitized dialysis patients. Increased waiting time is associated with increased morbidity and mortality among these patients. Thus, there is a need to further…
General hypothesis of the study is that the Equator day care treatment results in a significant improvement on indicators of mental health and social integration, compared to a control group consisting of respondents that did not receive Equator day…
An active revascularization strategy, i.e. recanalization of a CTO, might improve function in non-infarcted hibernating myocardium and promote infarct healing at the border zones. These effects may attenuate the remodeling process, which may lead to…
In each stratum of probability there is a clinically and statistacally significant difference in the functional ability and disease activity score over time (area under the curve) and progression of radiological joint damage after 1 year of follow-…
1. Cognitive behavioural group therapy is more effective than no intervention in prevention of social anxiety and related psychological problems; 2. Computer-based BiasRetraining is more effective than no intervention in prevention of social anxiety…
The primary objective of this test series will be to gain experience and provide long-term safety using a transcutaneous titanium port as an access port for gastrostomy (T-Port) in the context of Duodopa treatment of severely afflicted PD patients.
The aim of the study is to determine the dose-limiting toxicity (DLT) and maximum-tolerated dose (MTD) of irinotecan and cisplatin with concurrent thoracic radiotherapy in patients with LD-SCLC as a once every three weeks schedule.
To reduce cumulative radiation dose in the rectum in prostate cancer patients who are treated with curative intent using external beam radiotherapy. We will investigate whether position correction based on implanted gold markers or re-planning based…
HbA1c can improve in type 1 diabetes patients who continuously use the Paradigm® REAL-Time system.
Diagnostic uncertainty in patients with complaints of shortness of breath presenting to the Emergency Department of a hospital may delay treatment and proper care. In patients with shortness of breath due to heart failure increased plasma levels of…
1. It is hypothesized that participation in the Active plus program contributes to an increase in physical activity behaviour among older adults; 2. Additionally receiving physical and social environmental information results in an extra increase…
Therapeutic footwear of which adequate off-loading properties are guaranteed and monitored by dynamic plantar pressure assessment will result in a reduced plantar re-ulceration rate in diabetic patients with prior plantar foot ulceration compared to…
The use of parenterally administered LEV in neonatal epileptic seizures, detected electrographically, with or without clinical signs, will be safe, and pharmacokinetic and –dynamic properties of the use in neonates will be determined.
The specimen contains less evaluable endometrium after SIS than before SIS.
Intraneural injection of anesthetics in upper and lower extremity blocks increases the risk of neurological damage.
We hypothesise that bacterial translocation is the least in open colectomy followed by laparoscopic colectomy starting the devascularisation on the left side followed by laparoscopic colectomy starting the devascularisation on the right side. The…
According to the current national guidelines, as formulated by the Dutch Society of Cervical Pathology and Colposcopy in 1995, the follow-up in women treated for high grade Cervical Intraepithelial Neoplasia lesions consists of cervical cytological…
The primary objective of this trial is to validate the screening potential of NT-proBNP in a population of low to intermediate risk patients, i.e. patients with zero to two cardiac risk factors, scheduled for vascular surgery. The secondary…
De dosering misoprostol, die wordt toegediend bij de beeindiging (Eng: TOP) van de zwangerschap in het eerste trimester kan mogelijk verlaagd worden van 800 microgram naar bv 600 of 400 microgram als er gebruik wordt gemaakt van een rescue…
1. a. Does influenza vaccination in SLE and Wegener patients result in a decreased humoral immune response compared to healthy age-matched controls?; b. Does influenza vaccination in SLE and Wegener patients result in a decreased cellular immune…