31 results
Daily use of pre-thickened oral nutritional supplements for 12 weeks will have a positive effect on body weight of older nursing home residents with dysphagia and malnutrition (risk) as compared to standard nutritional - and dysphagia management
The relative risk of developing macular edema in diabetics after cataract surgery is enhanced.
Chronic allograft nephropathy is the main cause of long-term renal transplant failure. The pathogenesis involves amongst others calcineurin inhibitors. We performed a multicenter randomized trial to study the effects of withdrawal of ciclosporin (…
rt-PA administration by retinal branch vein way in CRVO patients improves final BCVA.
we hypothesize that an electronic nose can discriminate the VOC pattern in exhaled breath between patients with colorectal cancer and healthy controls.
Primary objective: To assess the efficacy of thromboprophylaxis with high prophylactic dose LMWH as compared with standard care without systemic thromboprophylaxis in children treated for primary ALL. Secondary objectives: 1. To assess the safety…
The aim of this study is to compare the efficacy of EBRT versus SEMS insertion for palliation of dysphagia symptoms in patients with esophageal cancer
Based on the results obtained in our previous study (Ruiter, Kolk, Rietveld, Dijkstra & Lotgering, 2011), we hypothesise that: - The experimental changes to the scenarios and new quantitative scoring procedure of the Amsterdam-Nijmegen…
To determine whether a second dose of IVIg in GBS patients with a poor prognosis improves functional outcome after 4 weeks. Secondary outcomes include functional outcome after 8, 12 and 26 weeks, duration of mechanical ventilation, length of…
1. It is hypothesized that participation in the Active plus program contributes to an increase in physical activity behaviour among older adults; 2. Additionally receiving physical and social environmental information results in an extra increase…
Nebulizing amoxicillin clavulanic acid is more effective for reaching amoxicillin levels in sputum > MIC90 than amoxicillin clavulanic acid given by oral or intravenous administration.
Antipsychotics (haloperidol) can cause acute changes in cardiovascular functions, metobolic parameters and platelet aggregation in elderly patients.
To develop a dosing nomogram of irinotecan in patients homozygous polymorphic for UGT1A1*28 and/or UGT1A1*93 in order to reduce the incidence of severe irinotecan-associated toxicity, defined as febrile neutropenia in the first 2 cycles (amendment…
The RAINBOW study: Rheumatoid Arthritis ImplemeNtation of Biological dose Optimization in real World
We hypothesize that a multifaceted implementation strategy can stimulate the use of tight control and bDMARD dose optimization in clinical practice, measured by decreased bDMARD use and non-inferiority on disease activity at 18 months.
Does lipid accumulation in skeletal muscle and the heart effect mitochondrial function in relation to insulin resistance?
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We expect that preoperative and postoperative cooling will reduce swelling faster, reducing the time to surgery and time to discharge, respectively.
we hypothesize that an electronic nose can discriminate the VOC pattern in exhaled breath between patients with Head and Neck Cancer from healthy controls.
Augmentation of the maxilla with calvarial bone has a lower complication rate than iliac crest bone.