1859 results
We hypothesized a beneficial effect of IUI in couples with an isolated cervical factor. Furthermore we hypothesized that the post-coital test can identify those couples who would benefit from IUI without ovarian hyperstimulation.
Patients with Type 2 diabetes have been shown to have an increased risk for developing cancer, especially obesity related cancers. There is some evidence that within the class of sulfonylureas there is a difference in cancer risk; gliclazide could…
the aim of this study is to compare two strategies that present a large contrast in the stimulation dosage, i.e. a high dosage of stimulation versus a low dosage of stimulation. Our study is designed to objectively compare the ongoing pregnancy rate…
Addittional training of teachers will result in greater effect-sizes for a school-based child intervention program for childhood behavior problems. Assessment of stepped-care child, teacher and parent intervention.
1. The intervention 'Happiness Route' is effective in promoting positive mental health in comparison to a control condition that consists of optimized care-as-usual; 2. In comparison to the control condition, the intervention '…
The bioavailability and effectiveness of vitamin K tablets and solution are comparable.
Our primary outcome is change in suicide ideation in patients. We hypothesise that, as a result of the improved skills and confidence of healthcare professionals in the experimental condition due to the intervention, suicidal patients are better…
This study will use a Randomized Controlled Trial (RCT) to evaluate the effectiveness and underlying mechanisms of the video game Mindlight, a newly developed anxiety-reducing training for children. Mindlight and a control game will be played for…
In this project the hypothesis is tested that the community pharmacist-led CATI care programme in patients using cardiovascular medication, will have a beneficial effect on patients’ adherence to cardiovascular medication and improves clinical…
We hypothesise that the Taperloc BoneMaster coated stem is equal or better than conventional porous coated or cemented stem focussing on implant ingrowth and bone remodelling.
The experimental group 2 (addition of action plans) will outperform the experimental group 1 (no action plans) with 10% at the last post-test after 12 months.
Life review therapy will have a positive effect on the level of depressive symptoms of nursing home inhabitants.
Care providers are more likely to adhere to clinical practice guidelines when they receive guideline-based decision support by an electronic system.
To investigate the difference in effectiveness of methylphenidate (MPH) in the treatment of adult ADHD patients with and without comorbid cocaine dependence.
In this study, we expect to decrease the number of referrals and repeat smears by immediately referring those women who are positive for hrHPV with mildly abnormal smears for colposcopically-directed biopsies. Thus, for the remaining women with BMD…
End stage kidney disease (ESKD) ranks among the most severe chronic non-communicable diseases with an unmet medical need, given the high (between 10% and 20%) and stable annual mortality rates in ESKD patients treated with dialysis. Kidney…
In general practices, proactive care for potentially frail older people with the use of Utrecht Periodic Risk Identification and Monitoring (UPRIM) and the use of a Geriatric Nurse Primary Care (GNPC) will result in better daily functioning in…
Pain (physical discomfort) and challenging behavior are highly prevalent in nursing home residents with dementia. It has been shown that pain is undertreated in this group, and that psychosocial interventions for behavioral problems are, allthough…
To assess whether temporary discontinuation of antihypertensive therapy in mildly cognitively impaired older patients on antihypertensive treatment improves cognitive and psychological functioning.
Despite appropriate antimicrobial therapy and supportive care, septic shock is still a major cause of mortality and morbidity. Within the last decade, a broad body of evidence suggests a potential role for mesenchymal stromal cell (MSC, a…