3394 results
In general practices, proactive care for potentially frail older people with the use of Utrecht Periodic Risk Identification and Monitoring (UPRIM) and the use of a Geriatric Nurse Primary Care (GNPC) will result in better daily functioning in…
Previous randomised trials have shown the efficacy of etanercept in RA patients. In this study we will evaluate the respons of etanercept in anti-TNF naive patients compared to patients who have failed other anti-TNF. We will look for clinical…
Donor-specific antibodies form a significant barrier in transplantation of highly pre-sensitized dialysis patients. Increased waiting time is associated with increased morbidity and mortality among these patients. Thus, there is a need to further…
Pain (physical discomfort) and challenging behavior are highly prevalent in nursing home residents with dementia. It has been shown that pain is undertreated in this group, and that psychosocial interventions for behavioral problems are, allthough…
To assess whether temporary discontinuation of antihypertensive therapy in mildly cognitively impaired older patients on antihypertensive treatment improves cognitive and psychological functioning.
Our first hypothesis is that in the two exisiting case management models, the persons with dementia will have less behaviour and mood problems than persons receiving usual care and informal caregivers experience better mental health compared to…
There is no difference between CT- and MRI-based Patient specific matched instruments for total knee arthroplasty
Despite appropriate antimicrobial therapy and supportive care, septic shock is still a major cause of mortality and morbidity. Within the last decade, a broad body of evidence suggests a potential role for mesenchymal stromal cell (MSC, a…
Providing feedback on practice patterns and practice variation will reduce variation between hospitals
Monotherapy with aspirin or oral anticoagulation after TAVI is safer than the addition of clopidogrel for 3 months, without being less clinically beneficial.
Recent experimental and clinical data showed that the noble gas helium protects against myocardial reperfusion injury in rabbits in vivo and induces late preconditioning in rat hearts. It has also been demonstrated that another noble gas, xenon, can…
1. What is the effect of Cognitive Behaviour Therapy in severely fatigued disease-free cancer patients on fatigue, functional impairment and psychological well-being, compared to patients waiting for this treatment? 2. Is the effect of Cognitive…
Manual negative pressure wound therapy is safe and is more effective than standard gauze dressing, in terms of duration of treatment and number of wound dressings.
Two hypotheses will be tested. First, we expect parents in the experimental group, who drink as well as those who abstain from alcohol, to use more alcohol-specific socialization strategies than parents in the control group. Second, we expect that…
We aim to compare the effectiveness, feasibility and safety of both metformin and sitagliptin in patients with TIA or minor ischemic stroke and impaired glucose tolerance. We will assess whether a slow increase in dose of metformin and better…
The two strategies (Venlafaxine and subsequent Lithium addition in non-responders to Venlafaxine; Imipramine and subsequent Lithium addition in non-responders to Imipramine) are comparable in efficacy and time to response.
Formalization of the current guidelines on VTE treatment duration with VKA, by means of using a VTE recurrence prediction model in patients with venous thrombo-embolism, will optimize its cost-effectiveness compared to care-as-usual. Only patients…
The current study was developed to evaluate the effect of the modi drawings on treatment outcome. We hypothesize that patients within the art modi group have more knowledge of their modi, which in turn will lead to a better understanding of ¡°why…
Customers of the experimental food banks (poster) use selftests more often as prevention than customers of the control food banks (no poster).
Early, aggressive treatment of rheumatoid arthritis with DMARDs has been proven to lower disease activity and suppress radiologic progression. Moreover, combination therapy is shown to be superior to monotherapy. The COBRA therapy is effective in…