47 results
The primary objective of the LION RCT is to assess the (cost-)effectiveness of a personalized, live-remote exercise intervention for cancer survivors on Health-Related Quality of Life (HRQOL) and the participants* main, self-reported side-effect.…
Primary: To assess the effects of a 2-week preoperative vegan diet in comparison to an omnivorous diet on protein synthesis rates in Hoffa*s fat pad, synovium, bone, ligaments, menisci, and cartilage in older adults with knee osteoarthritis…
Primary:1. Do twelve weeks of MegaPower training effectively accomplish patient-tailored participation and activity goals in ambulant children with CP, when compared to their usual care? Secondary:1. Do twelve weeks of MegaPower training improve…
To investigate the impact of BT as compared to standard of care in severe asthma patients that remain uncontrolled despite standard treatment including adequate doses of inhaled preventer therapies with or without biologics on:(1) rate of…
We aim to lay the fundament of novel interventions by gaining an in-depth comprehensive understanding of individual differences in the overnight adaptation of emotional memory and malleability thereof by noradrenergic modulation.
Evidence showing which aftertreatment protocol is best for both fracture healing and functional outcomes for patients with Displaced Intra-Articular Calcaneal Fractures (DIACFs) is lacking. This study has the aim to answer the question whether…
To evaluate and compare the survival outcome of patients with first recurrence of glioblastoma undergoing surgical debulking/resection followed by either implantation of the SC9 device and repeat BBB opening in association with carboplatin…
The aim of this randomized trial is to appraise the impact of IABP in the treatment of early stages of cardiogenic shock, irrespective of etiology. Findings of this randomized trial may enhance clinical decision making regarding the use of MCS in…
The main objective is to study whether flashforward (FF) EMDR alone is effective in reducing anxiety symptoms in ICD patients.
Primary Objective:1) To determine the efficacy of personalized progressive resistance training (PRT) on muscle strength of elbow flexors in children and adolescents with Spinal Muscular Atrophy and Congenital Myopathy compared to usual care…
Primary Objective: • To assess whether the food supplement Endocalyx lowers blood pressure in patients with treatment resistant hypertension.Secondary Objectives: • To study the effect of Endocalyx on office blood pressure and 24-hour blood pressure…
The study aims to assess the safety and efficacy of the Freesolve scaffold in de novo coronary artery lesions compared to the Xience coronary stent system during standarfd clinical use. This is in the context of the MDR and the legal obligation to…
Primary Objective: What is the difference in the effectiveness of the Food Pharmacy Program in glycaemic regulation compared to nutrition coaching performed by dieticians after three months in overweight adults with type 2 diabetes? Secondary…
The proposed study aims to examine the efficacy and process of an individualized (vs. standardized), comprehensive and family-centered neuropsychological intervention for pediatric brain tumor patients experiencing neuropsychological problems. The…
The primary objective of this study is to evaluate the cost-effectiveness of individual ST (max. 40 sessions) vs. UC in patients with treatment-resistant anxiety disorders from a societal perspective. The second objective is to explore whether…
The main objective is to investigate the effect of a 16-week AET or CBT program on fatigue in patients with MG, compared to care as usual.
To investigate if resection with a margin, that is significantly beyond the radiological contrast enhancement, improves overall survival in selected patients with glioblastoma.
To investigate the effectiveness of an anti-inflammatory diet in reducing pain symptoms among patients with endometriosis and to explore whether the addition of CBT enhances this pain-reducing effect apart from the effect of CBT alone. The secondary…
The primary aim of this clinical trial and healthcare evaluation (in Dutch: Zorgevaluatie) is to compare the diagnostic value of two diagnostic EEG strategies (repeated EEG with and without prior sleep deprivation) frequently applied in current…
The aim is to reduce SSI in PWT2D by implementing a proactive basal-bolus insulin regimen, compared to a widely used reactive sliding scale regimen. It is hypothesised that a proactive basal-bolus insulin regimen targeting glucose levels of 3.9-10…