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Game Ready continuous-flow cryo- and cyclic compression therapy after fracture treament of the hip: a prospective multicenter, open-label, multicenter, randomized, controlled, clinical trial on postoperative effects on pain.

The goal of the study is whether to establish if application of combined cyrocompression therapy directly postoperative after hip fracture surgery results in a significant reduction in painperception en whether this reduces the morfine consumption.…

Use of the Auditory Biofeedback system to improve a patient*s partial weight bearing compliance: a feasibility study

Primary Objective: To determine whether it is feasible to use an ABF device to lower the amount of incorrect steps. Incorrect steps are the steps exceeding the maximum allowed load or being below the minimum load.The specific research question that…

Uncemented tibial component fixation in total knee replacement using porous titanium. A Randomized RSA Study

The aim of this study is to compare the early post-operative migration as measured by Roentgen Stereophotogrammetric Analysis (RSA) of the uncemented tibial component with plasma spray coating with the uncemented porous coated tibia component.

A prospective randomised Rontgen Stereophotogrammatic Analysis (RSA) study using the uncemented Trident Tritanium acetabular component and the uncemented HA coated Symax hip stem in a single centre.
Assessment of implant migration, bone remodeling and clinical function.

The goal of this clinical investigation is to assess the early migration and bone remodeling of the Symax hip stem and the Trident HA coated or Trident Tritanium acetabulum component with RSA and 18-F PET CT Also the sensitivity of the RSA…

A prospective randomized trial comparing the effect of two different methods of anesthesia for reduction of displaced distal radius fractures; haematoma block versus peripheral nerve block at the elbow

To compare the effect of two different methods of anesthesia on painsensation (VAS score) during fracture reduction.

Dorsal spondylodesis in adolescent idiopathic scoliosis: proximal fixation with screws versus claw construct

The main objective is to compare the coronal Cobb angle correction of proximal hook claw fixation versus proximal pedicle screw fixation after two years of follow-up. The secondary objectives of the study are: comparison of coronal Cobb angle…

The effect of Hoffa*s fat pad resection in total knee arthroplasty on functionality and pain: a double blind, randomized clinical trial

The main objective of this study is to test if resection of Hoffa*s fat pad in total knee arthroplasty leads to a greater range of motion and if resection leads to a faster recovery of normal walking gait and preferred walking speed post operatively…

PROMOTION-trial: A PROspective randomized Multicenter trial for the treatment of dislocated 3- and 4-part proximal humerus fractures: Open reduction and internal plate fixaTION versus intramedullary nailing.

Goal of this trial is to point out the surgical intervention with the best functional outcome.

Antibiotic prophylaxis and prevention of wound infections following implant removal after foot, ankle and lower leg fractures

In light of the above, our objective is to study the (cost-) effectiveness of a single intravenous gift of antibiotic prophylaxis with a firstgeneration cephalosporin prior to implant removal following surgical fixation of foot, ankle and/or lower…

Effect of local anesthetic dose versus volume on block duration of single shot ultrasound-guided axillary brachial plexus block with mepivacaine.

Primary objective: to determine the effect of mepivacaine dose and volume on the duration of sensory axillary brachial plexus block (overall and individual nerves).Our hypothesis (H0) is that there is no difference (less than 60 min) in duration of…

Pain management after operative treatment of extremity fractures, a randomized clinical trial

The primary objective of this study is to determine (differences in) patient satisfaction with pain relief and pain intensity (Numeric Rating Scale) using a step 1 vs. a step 2 based analgesic regimen.The secondary objective is to determine…

Optimizing the intermanual transfer effects after training with a prosthetic simulator

The objective of this study is to determine the optimal myo-electric prosthesis training for obtaining the largest transfer effect. Here fore we plan to execute three experiments. At first it needs to be revealed which trainingtasks leads to the…

Radiological evaluation of CT based vs MRI based Signature* for total knee arthroplasty

PrimaryTo evaluate the alignment of the Signature* CT-based procedure compared to the Signature* MRI-based instruments.SecondaryTo evaluate the efficacy of the CT-based Signature* procedure in terms of operation time compared to the Signature* MRI-…

Intermanual transfer using mental imagery in prosthetic training

The objective of this study is to determine the surplus value of mental imagery on myo-electric prosthesis training Here fore we plan to execute two experiments. The goal of the first experiment is to test if intermanual transfer effects of able-…

Anterior cruciate ligament CT study:
Transtibial, anteromedial portal, tape locking screw reconstruction technique

The main objective of this study is to compare the femur tunnel positioning after AMP, TLS and TT reconstruction techniques. We will also look at the relation between tunnel positioning and tunnel widening.

Comparative roentgen stereophotogrammetry analysis (RSA) between the conventional Mallory- Head stem in primary uncemented total hip replacement compared to two shorter variations

Objective: To perform a comparative assessment between the clinical, bone remodelling, and radiographic outcomes (as measured with RSA) of the conventional Mallory-Head stem compared two shorter versions of Mallory-Head stems in patients undergoing…

Joint distraction (KJD) in treatment of knee osteoarthritis: cartilage changes in a comparison with a presently applied surgical alternative: high tibial osteotomy (HTO)

1. To compare cartilage changes after KJD and after HTO, based on MRI, radiographs and biomarkers, evaluated 2 years post treatment. 2. To compare clinical efficacy after KJD and after HTO during 2 year follow-up by a questionnaire (KOOS; for pain,…

Kinetic motor imagery training during immobilization to improve wrist functional outcome after a distal radius fracture in women of 45-75 years of age

The objective is to improve the functional outcome in distal radius fracture patients, specified as an increase in function, dexterity, grip strength, range of motion, and decrease of pain.

Primary stability of cemented vs uncemented stems in revision total knee arthroplasty measured with RSA: a randomised controlled trial.

Which technique, cementing or press-fit implanting, of the tibial and femoral stem of the Legion revision total knee prosthesis provides the most primary stability?

Wear analysis of cross-linked versus standard polyethylene F.A.L. acetabular cups in patiënts with symptomatic coxarthrosis: a randomized controlled trial

Primary goal: mean linear wear of the cross-linked polyethylene F.A.L. cup compared to the mean linear wear of the standard polyethylene F.A.L. cup at 5 years postoperatively. Secondary goals:1. mean linear wear (millimeters/year) at 1 year, 3 years…