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Randomised comparison of endoscopic trimodal imaging versus chromoendoscopy as surveillance strategy for neoplasia in ulcerative colitis

Comparing differentiation and detection of neoplasia in patients with ulcerative colitis undergoing surveillance, by ETMI and CE, in a randomised trial.

Colonoscopy with EndoCuff vs conventional colonoscopy
A randomized controlled trial

We aim to test the hypothesis that EndoCuff improves totaal number of adenomas detected and ADR compared with regular colonoscopy. In other words, we'll study if the Endocuff colonoscopy detects more polyps.

The influence of micrometastases on prognosis and survival in stage I-II colon cancerpatients: the EnRoute+ study

The purpose of the study is to delineate the upstaging percentage of pN0 patients by detection of micrometastases (pN0micro+) and evaluate the benefits from adjuvant chemotherapy on disease recurrence in pN0micro+ CC patients.

Endoscopic screening for dysplasia in patients with longstanding ulcerative colitis: Classical chromo-endoscopy versus NBI, FICE and I-scan

Assessment of the detection of neoplastic lesions in patients with longstanding ulcerative colitis, using different endoscopic imaging techniques: A: Chromo-endoscopy, methylene blue 0.1% (HDTV Olympus)B: HDTV Olympus colonoscopes and NBIC: Chromo-…

Endoscopic Tri-Modality Imaging (ETMI) for the detection of early colorectal neoplasia; a multi-center randomized controlled trial

The aim of this randomized controlled multi-center study is to establish whether ETMI improves the detection early colorectal neoplasia compared to standard video endoscopy in a non-expert setting and is effective in differentiating neoplastic from…

Endoscopic Tri-Modal Imaging (ETMI) for the detection of early neoplasia in patients with Barrett*s esophagus (BE) in tertiary referral centers; a randomized cross-over multi-center study.

Does ETMI improve the dysplasia in Barrett's esophagus?

Treatment of anal intraepithelial neoplasia in HIV-positive patients, a triple-arm randomized clinical trial

To establish the preferred treatment of AIN to prevent the development of severe anal neoplasia (persistent AIN III or anal carcinoma) in HIV+ MSM and HIV+ woman.

Three different limited bowel preparation regimes for CT colonography: evaluation of image quality and patient acceptance

To investigate what CTC iodine tagging-only bowel preparation gives a high image quality and readability of the CTC together with a high patient acceptance.

Chromoendoscopy in Lynch syndrome patients

The aim of this study is to determine whether chromoendoscopy, including polypectomy of all detected lesions, reduces the development of colorectal neoplasia in Lynch syndrome patients at follow-up endoscopy.

The effect of ContrAst media Temperature on patient comfort in Computed tomograpHYof the abdomen. (CATCHY trial)

Primary objective:- To evaluate pain and discomfort during and after injection of CM with varying temperatures (20° C and 37° C).- To evaluate the liver attenuation (HU) and image quality (IQ) using iodine injected with various temperatures (20°C…

Second and third look laparoscopy in pT4 colon cancer patients for early detection of peritoneal metastases; the COLOPEC 2 randomized multicentre trial.

The primary aim of this study is to determine the added value of third look DLS to detect PM at a clinically occult stage following a negative second look DLS.

Radioembolization with 166Ho-microspheres in elderly and/or fragile patients with previously untreated unresectable liver-only metastases of colorectal cancer, CAIRO7 study endorsed by the Dutch Colorectal Cancer Group (DCCG)

Primary objective:The objective of this randomized phase 2 study is to demonstrate efficacy of RE in terms of PFS in colorectal cancer patients with liver-only metastases who are candidates for palliative systemic treatment with capecitabine plus…

Dye chromoENDOscopy versus virtual chromoendoscopy for assessment of the ileo-anal pouch in patients with familial adenomatous POLyposis: a randomized controlled trial

The primary outcome of this study is the detection of clinical relevant adenomas (>= 5mm) in the ileal pouch.

Real-time use of artificial intelligence (CAD EYE) in the colorectal cancer surveillance of Lynch syndrome patients - an international multicenter trial

Primary Objective:- To compare adenoma detection rate (ADR) with versus without real-time automated detection (CAD EYE, Fujifilm)Secondary Objectives:- To compare the size, morphology and histology of adenomas detected and resected in both arms of…

Multimodal prehabilitation program in colorectal cancer patients to improve functional capacity and reduce postoperative complications.

To design, implement and test a multimodal prehabilitation program in order to lower the complication rate and improve recovery rate for patients undergoing colorectal surgery for colorectal cancer by enhancing functional capacity (cardiopulmonary…

Rapid on-site evaluation (ROSE) vs. randomly collected samples from mediastinal and abdominal lymph nodes obtained by endoscopic ultrasound-guided fine-needle-aspiration

The goal is to investigate the added value of having a cytotechnician on-site while performing EUS-FNA of a lymph node.

The relationship between contrast media volume and tube voltage in computed tomography of the liver, for optimal enhancement based on total body weight: A randomized controlled trial. [COMpLEx trial]

The aim of present study is to investigate if adapting the dosing factor based on TBW and therefore the CM volume to the tube voltage used, results in a more homogeneous liver enhancement. We hope to find a more homogeneous enhancement between…