126 results
Compare usual care in patients with treatment resistant heart failure with additional ultrafiltration by peritoneal dialysis.
To evaluate the long-term safety and efficacy of two concentration-controlled everolimus regimen in de novo liver transplant recipients at Month 36 post-transplantation.
Main objective: Does the use of the extravesical ureterovesicostomy reduce the incidence of PCN placement, and urological complications?Secondary objective: Does the use of the extravesical ureterovesicostomy reduces the rate of re-operations and re…
Objective: To investigate the safety and efficacy of a therapy consisting Everolimus and corticosteroids maintenance immunosuppressive regime twelve months after renal transplantation in recipients of donor kidney graft on graft function and acute…
Primary objectivesThe primary objective of the study is demonstrate that at least one of the sotrastaurin treatment arms is non-inferior to the active control regimen myfortic + tacrolimus with respect to composite efficacy failure (treated BPAR of…
To develop a workable and effective programma to encourage the self management abilities of people with progressive chronic kidney disease stage 1-4. The evaluation consists of a process- and an effect evaluation.The process evaluation will evaluate…
To investigate if determining dry-weight with the assistance of bioelectrical impedance analysis compared to the current practice will result in a better blood pressure control.
The primary objective of this study is to evaluate the long-term safety and tolerability of the TAK-491CLD FDC in comparison to the OLM/HCTZ FDC in hypertensive subjects with moderate renal impairment.
* To evaluate the long-term efficacy of FCM (using targeted ferritin levels to determine dosing) or oral iron to delay and/or reduce erythropoiesis stimulating agent (ESA) use and/or other anaemia management options in NDD-CKD subjects with iron…
The primary objective is to assess whether renal denervation added to usual care compared to usual care alone reduces BP (office based BP and 24-h ambulatory BP-monitoring) both in subjects with a SBP level above 160 mmHg as well as subjects with a…
To study if regular follow-up of PD patients with testing of their theoretical and practical knowledge (hereafter called *new type of follow-up*) can reduce the incidence of peritonitis, reduce the technique failure rate related to peritonitis, and…
Primary : To evaluate the safety and tolerability of single oral doses of LY3045697 administered to healthy subjects Secondary : To investigate the pharmacokinetics of single oral doses of LY3045697 administered to healthy subjects Exploratory : To…
To evaluate the use of concentration-controlled everolimus, with the reduction or the elimination of tacrolimus, to provide superior renal function and to provide non-inferior rates of the composite efficacy endpoint compared to the tacrolimus…
Primary: To evaluate the safety and tolerability of LY3045697 after multiple oral dosing in healthy subjectsSecondary: To investigate the pharmacokinetics of LY3045697 after multiple oral dosing in healthy subjects
A 6-month study of efficacy and safety comparing concentration-controlled Certican® with MSCs to Certican® with standard tacrolimus in renal transplant recipients
To test the efficacy of renal sympathetic denervation therapy with a special focus on preservation of renal allograft function.
The overall aim of the project is to improve health outcomes and autonomy of CKD patients by testing a self-management care model regarding hypertension control. Furthermore, this study will investigate the impeding and facilitating factors for…
Primary objective: To demonstrate superior renal allograft function in de novo renal transplant recipients after early CNI to everolimus conversion assessed by Glomerular Filtration Rate (eGFR) estimated by the Modification of Diet in Renal Disease…
To investigate if a dosage advice for darbepoetin and iron generated by a pharmacist leads to an increase of haemodialysis patients whose haemoglobin values lie within the target range, compared to dosage of darbepoetin by the nephrologist alone.
The present study will investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of ARA 290 administered intravenously to patients with ESRD.