15 results
zie NL
To explore the effect of stress on the neural correlates of emotion regulation, we will combine sophisticated behavioural tasks in a functional magnetic resonance imaging (fMRI) setting with a well-established stress-induction procedure.
First, we want to examine whether a CBM training aimed at inducing positive appraisal style (positive CBM-app) can alter dysfunctional appraisal styles in PTSD patients. Second, we want to examine whether this CBM-app training has an effect on PTSD…
The main objective of the study is to determine whether, and if so, to what extent, there are differences in memory vividness, detail and certainty between OCD patients, another anxiety disorder patients and healthy subjects in a repetitive checking…
The present study will examine whether administration of a beta blocker (propranolol) and cortisol (hydrocortisone) to a healthy male population during retrieval of emotional memories in healthy subjects will lead to long term changes in these…
The properties of CBD, namely potential effects on variables pertaining to fear extinction and potentially on fear retention/reinstatement while having non of the problematic side-effects found in Δ9-THC, make CBD plausibly preferential over Δ9-THC…
The aim of this experiment is to determine the differential effects of noradrenaline and cortisol on memory accuracy versus generalization and to investigate the divergent effects of these stress mediators on the neural mechanisms underlying the…
The primary objective is to assess the causal role of the human amygdala in fear learning, by indexing the impact of TUS targeting the amygdala on physiological markers of fear. The secondary objectives are to (1) discern the neuromodulatory effects…
The aim of this experiment is to investigate whether training reappraisal will prevent stress-induced impairments in effective emotion regulation, and if this training effect is associated with reduced negative effects of acute stress on PFC…
In this study, we aim to prove a double dissociation between the contribution of dopamine and norepinephrine during the acute stress response.
The aim of this study is to investigate the combined and independent roles of the two major stress hormones, noradrenaline (NA) and cortisol, in intentional forgetting under stress using a pharmacological manipulation. As such, our aim is to…
To investigate the effects of aPFC-SMC phase-coupled tACS on exposure for SAD.
We aim to lay the fundament of novel interventions by gaining an in-depth comprehensive understanding of individual differences in the overnight adaptation of emotional memory and malleability thereof by noradrenergic modulation.
In this project, pharmacotherapy will be used to target the molecular basis of memory consolidation in the acute trauma phase to prevent the intrusive aspects of traumatic memories from forming. An excellent candidate to pharmacologically manipulate…
The properties of CBD, namely potential effects on variables pertaining to fear extinction and potentially on fear retention/reinstatement while having non of the problematic side-effects found in *9-THC, make CBD plausibly preferential over *9-THC…