19 results
The aim of this study is to compare the effects of anterior cervical discectomy versus percutaneous plasma discectomy on pain, on global perceived effect, functional status and health-related quality of life in a group of patients with cervical…
Investigate the value of percutaneous radiofrequency heat lesion applied to the ramus communicans; more specifically try to determine if a significant and long lasting pain reduction can be obtained as compared to a sham-operated group. In addition…
To assess the analgesic efficacy, safety, and tolerability of once daily orally administered GRT6005 in a total of 3 fixed doses (i.e., 200 µg, 400 µg, and 600 µg GRT6005) compared to placebo in subjects with moderate to severe chronic LBP.
1. To compare the efficacy of tofacitinib, in doses of 2 mg, 5 mg, and 10 mg BID versus placebo on the ASAS20 response rate at Week 12 in subjects with active AS that have had an inadequate response to previous treatment.2. To estimate the placebo-…
Assessing the effectiveness and safety of parecoxib compared to placebo in pain relief children undergoing scoliosis surgery
The primary objective is to gain insight into the effects of guided imagery on pain intensity in people with fibromyalgia. Secondary objective is to gain insight into the effects on self efficacy and functional status.
To show whether Active C disc prosthesis is more effective than anterior discectomy with or without interbody fusion 1 year after surgery. Moreover, the incidence of adjacent disc degeneration will be evaluated 5 years after surgery.
The main objective is to gain insight into the effects of guided imagery on pain, self efficacy and functional status of people with fibromyalgia and into the relationships between these outcome variables.
The primary aim of the study is the prospective recording and follow-up of the clinical and radiographic data of patients who received soft tissue interpositional arthroplasty with Graft Jacket® as a treatment of painful glenohumeral osteoarthritis…
The objective of this study is to prove that a single injection of PRP in the CEO decreases pain and duration of the condition in patients with chronic lateral epicondylitis compared to injection with lidocaine and corticosteroids.The specific…
To compare functional recovery of the patient and the fusion status of ceramic cages versus PEEK cages on the short and long term.
(1) To phenotype chronic low back pain patients in terms of endogenous modulation of pain, central sensitization/facilitation, and the presence of a neuropathic pain component;(2) To assess the effect of a three-month treatment with tapentadol on…
To assess if a continued rehabilitation program in the first six weeks post-surgery for patients following a first time is morecost-effective as compared to no further treatment after discharge from the hospital an economic evaluation alongside…
To assess whether patients receiving simple hallux valgus surgery ambulate independently earlier after spinal anesthesia combined with LIA, compared to popliteal blocks. We hypothesize that both groups will demonstrate sufficient pain relief.
To determine whether intraoperative epidural analgesia is superior to placebo in reducing wound pain in patients after decompressive lumbar spine surgery, and to determine whether opioid use in the 2 days after surgery is significantly higher in the…
The primary objective of this study is to assess the effectiveness and cost-effectiveness in terms of the number of surgeries prevented of a combination therapy versus usual care.The secondary objective of this study is to assess the effectiveness…
Primary Objective:Double-blind period : Evaluate the effect of SRP-4045 and SRP-4053 (combined-active group) compared to placebo on ambulation, endurance, and muscle function, as measured by the 6MWTSecondary Objectives:- Double-blind period:…
The primary objective is to investigate whether the use of patient-specific cutting guides for an open wedge high tibial osteotomy (HTO) provide a more accurate correction relative to the preoperative planning compared to the conventional osteotomy…
With this research, we are examining the impact of skin displacement in individuals with chronic low back pain. We are investigating its effects on the mobility of the back and hip, as well as its influence on muscle activity in the back and…