63 results
The primary objective is to assess feasibility of a food supplement (multispecies probiotic) placebo-controlled, randomised controlled, double blind intervention in pregnant women in their late second/third trimester of pregnancy, to reduce symptoms…
In this trial we now aim to investigate comprehensively the effect of riboflavin supplementation on the abundance of F. prausnitzii and on other members of the gut microbiota in faeces of healthy volunteers. Additionally we will assess whether…
The purpose of the present study is to investigate the effects of light therapy (with two different light boxes) on depression in people with intellectual disability (IQ *70 ) compared to standard care (care as usual).
Primary objective:- To investigate if exercise can modulate neurogenesis and angiogenesis in vivo, and whether this is associated with changes in hippocampal function, such as pattern separationSecondary objectives:- To assess whether exercise-…
Study I aims to explore dysregulation of biological stress systems among traumatized youths with and without ID in residential care, and compare them with a healthy control group. Study II aims to conduct a randomized controlled trial (RCT) to test…
Primary objective: Investigate the effects of acute stress on resting state and task-induced connectivity in the brain of healthy individuals and unaffected siblings of schizophrenia patients. Secondary objectives: - Correlate the endocrine stress…
To assess whether temporary discontinuation of antihypertensive therapy in mildly cognitively impaired older patients on antihypertensive treatment improves cognitive and psychological functioning.
Phase 1: Investigate a possible suppressing effect of prophylactic paracetamol use in adults on the response of the hepatitis B vaccination. Phase 2: Study the association between timing of the use of paracetamol during hepatitis B vaccination and…
to develop a *two hit* in vivo autologous RBCs transfusion model in healthy male volunteers.
To compare the digestibility, bioavailability and subsequent muscle protein synthetic response to casein, with casein protein provided in an isolated manner versus casein in a milk matrix, in healthy elderly subjects
To investigate whether twice daily local (calf muscle) NMES attenuates muscle loss during 2 weeks of unilateral ankle immobilization due to an ankle fracture.
Primary objective: - Investigate the effects of childhood maltreatment on basal and stress-induced in vivo metabolite concentrations in the brain measured with 7T-MRS. Secondary objectives: - Correlate the endocrine, autonomic and subjective stress…
The primary objective is to determine an effect of sleep deprivation on CSF Aβ42 levels in humans.Secondary objectives: -Effect of unrestricted sleep on CSF Aβ42 levels.-Effects of unrestricted sleep and sleep deprivation on other known AD…
To study the effectiveness of vitamin B12 supplementation on decreasing fatigue in IBD and IBS patients with increased or severe fatigue and normal vitamin B12 levels.
The primary objective of the study is to investigate whether carbohydrate co-ingestion augments the in vivo postprandial muscle protein synthetic response after protein ingestion and whether this response is differs between young and elderly…
The central hypothesis of Switchbox is that control of homeostasis by the hypothalamus will be better preserved in the offspring of long-lived sibling who age in better health compared to their partners that show *regular* ageing. This, we…
Our unique project is based on an ongoing European prenatal stress research focusing on the effect of prenatal stress on early sensory-cognitive development. We capitalize on the methodologically sound maternal and infant physiological measures…
The primary objective of the study is to investigate whether local insulin supplementation augments the in vivo postprandial muscle protein synthetic response after protein ingestion and whether this response is differs between young and elderly…
The primary objective of this clinical trial is to determine the effects of high oral and gastric stimulation on subsequent food intake. The secondary objectives are:- What is the effect of oral stimulation (low vs. high) and different gastric…
To investigate the effects of 5 days of one legged knee immobilization with or without daily NMES on quadriceps CSA, lean mass and muscle fiber characteristics.