161 results
To compare the effect of umbilical cord clamping after cardiopulmonary stabilisation (Physiological Based Cord Clamping; PBCC) to standard care (Time Based Cord Clamping; TBCC) on intact survival and health care costs in preterm infants.
To assess if prompt start of labour (<16 hours) of a fetus with RFM, based on CPR <1.1 in term pregnancy will improve the neonatal outcome (including perinatal mortality and long-term (neurodevelopmental) outcome) and maternal outcome…
The primary objective of this study is to explore the effect of VR on pain during ECV. Secondary objectives are the rate of succesful ECV procedures and tot explore tolerability, faesibility and patient satisfaction of VR use.
The overall objective of the study is to investigate a lifestyle intervention for women with a pregnancy wish or pregnant women in their first trimester, and a high risk on perinatal morbidity because of (prepregnancy) overweight or obesity. With an…
This study has been transitioned to CTIS with ID 2024-513042-12-01 check the CTIS register for the current data. To perform a double-blind randomized placebo controlled multicenter study with darbepoetin in infants with MRI confirmed PAIS and to…
Does, in late preterm fetuses identified as small-for-gestational-age (SGA), timing of delivery based on abnormal umbilicocerebral ratio (UCR) improve neurodevelopmental outcome?
To investigate the effect of FCR during hospital stay, accompanied by FICare, on parental stress at discharge in parents of preterm (born before 37 weeks of gestational age) or ill (for instance with sepsis or small for gestational age) infants…
This study will evaluate if neonatal effects as described in previous studies are seen in delayed umbilical cord clamping in caesarean sections. Moreover, we will review the maternal effects compared to conventional cord milking in caesarean…
The effect of continuous care during childbirth care compared with current standard care, in which continuous guidance has not yet been achieved.
The main objective is to study the effect of the nutritional intervention versus the control product on white matter development (as assessed using tract based spatial statistics of fractional anisotropy) using a DTI scan at the corrected age of…
This study has been transitioned to CTIS with ID 2024-511322-31-00 check the CTIS register for the current data. To evaluate whether in newborns with asphyxia and early clinical signs of hypoxic ischemic encephalopathy, early postnatal allopurinol…
The aim of this study is to investigate if tocolysis with atosiban in late preterm birth (30 to 34 weeks) is (cost-) effective compared with placebo in improving neonatal morbidity and mortality.
To determine the effect of time restricted eating in gestational diabetes on glucose metabolism.
The primary objective is to demonstrate the superiority versus placebo of a 4 weeks intranasal OT administration on oral skills assessed by the Neonatal Oral-Motor Assessment Scale (NOMAS) in infants with PWS aged less than or equal to 3 months at…
Primary Objective: To evaluate whether PBCC results in a reduced incidence of pulmonary hypertension in infants with CDH 24hrs after birth.Secondary Objectives: To measure and monitor physiological parameters during transition to provide information…
It is hypothesed that intervention (bariatric surgery) compared with control (life style intervention program) will increase fertility measured by the healthy born baby rate after at least 37 weeks of gestation (primary end point) within 3 years…
To evaluate the efficacy and safety of intermediate dose LMWH versus fixed low dose LMWH in pregnant women with a history of previous VTE.
The purpose of this study is to assess the outcomes of monitoring the fetal condition with STV in cCTG compared to visual interpretation of the CTG in order to time delivery in pregnant women with severe, early-onset FGR.
The aim of this study is to investigate whether VR will decrease the request for labour analgesia. Primary outcome measure:* Request for labour analgesiaSecondary outcome measures:* Patient tolerability, feasibility and satisfaction of VR use (VR-…
To assess the effectiveness of a cerclage in women with a twin pregnancy with a midpregnancy short cervix compared to standard treatment (no cerclage) in the prevention of extreme preterm birth (PTB) < 28 weeks of GA.