50 results
First ObjectiveIn this study we compare a policy of labour induction at 41 weeks with a policy of expectant management until 42 weeks, with an outpatient check for CTG monitoring and ultrasound measurement in the 42nd week, with respect to the…
In view of this lack of evidence and strong practice variation we propose a randomized clinical trial in overweight and obese subfertile women, in which we compare the costs and effects of a six months structured lifestyle program, aimed at weight…
To investigate the effect of maternal hyperoxygenation with 100% in the second stage of labor and in the presence of abnormal fetal heart rate (FHR) patterns on fetal condition, instrumental delivery rate and free radical production. In case a…
1. To evaluate and compare the impact of hysteroscopic Essure® intratubal device placement and laparoscopic salpingectomy on IVF-ET outcomes of patients with hydrosalpinx.2. It is still uncertain whether laparoscopic salpingectomy for hydrosalpinx…
We will examine effectiveness of the internet-based self-help intervention compared to a waiting list control condition on (1) reduction of depressive and anxiety symptoms post intervention and 6 weeks post-partum and (2) improvement in perinatal…
To assess in term pregnant women with an unfavourable cervix (Bishop score < 6, Appendix1) the effectiveness of induction of labour with a transcervical Foley catheter as compared to induction with misoprostol.
The overall objective of this trial is to generate data on the ovarian stimulation profile obtained when Pergoveris® is started either on stimulation day 1 or stimulation day 6 in ART patients between 36 and 40 years of age (both inclusive). A…
To assess the effects of a screening policy for Q fever in pregnant women from areas with large numbers of Q fever cases on the pregnancy outcome and cost-effectiveness from a societal and health care perspective.
To evaluate the effectivity of the electrohysterogram (EHG) by means of a tocopatch electrode compared to tocodynamometry by means of an external tocodynamometer or intrauterine pressure catheter (IUPC) to monitor trial of labour (TOL) in patients…
Our unique project is based on an ongoing European prenatal stress research focusing on the effect of prenatal stress on early sensory-cognitive development. We capitalize on the methodologically sound maternal and infant physiological measures…
To assess in women with a request for pain relief during labour the cost-effectiveness of remifentanil patient controlled analgesia (RPCA) as first choice compared to EA.
The objective of this study is to gain insights into the value of the proposition *Origo* for women and their loved ones, medical staff and care institution.
The objective of this study is to determine whether retention of cerclage after PPROM improves latency (without a significant increase in chorioamnionitis) and lessens neonatal morbidity.
The primary aim of this study is to determine to what extent FBS is effective in preventing unnecessary operative delivery for CTG-suspected fetal distress. The secondary aims are to determine if FBS does not enhance poor perinatal outcome. Tertiary…
SIGnificance of routine Hysteroscopy prior to a first 'in vitro fertilization' (IVF) Treatment cycle
The aim of the proposed study is to assess whether diagnosing and treating unsuspected intrauterine abnormalities by saline infusion sonography and/or routine office hysteroscopy prior to a first IVF/ICSI treatment cycle improves the cost-…
Primary objective: To assess in term pregnant women with an unfavourable cervix (Bishop score < 6, Appendix1) the time interval between induction of labour and birth with a transcervical Foley catheter filled with 30mL compared to induction…
Our objective is to test the following hypotheses : - Hypothesis 1 (part 1 of the study): The stress reduction intervention has beneficial effects on subjective maternal emotional well-being, on objective maternal stress system measures (i.e., HPA-…
The following hypotheses will be tested:Hypothese a: Remifentanil PCA gives a better labour satisfaction than pethidine/meperidine i.m.Hypothese b: Remifentanil PCA gives a better pain-relief during labour, than pethidine/meperidine intramuscularly.…
To investigate the hypothesis that in women with a multiple pregnancy prophylactic use of a pessary will be effective in the prevention of preterm delivery and the neonatal mortality and morbidity resulting from preterm delivery. To assess in women…
The main objective of this study is compare the analgesic efficacy and safety of remifentanil, administered as patient-controlled analgesia (PCA), with epidural analgesia.