134 results
Primary Objective: The primary objective is to determine if AMG 827 is effective compared to placebo as measured by change in Asthma Control Questionnaire (ACQ) composite scores from baseline to week 12. Secondary Objectives: Evaluate the efficacy…
To study the effects of changing consultations by starting with the patients agenda on the enablement of children with asthma and their parents to bring forward their questions, worries, problems and beliefs.
To demonstrate the superiority of indacaterol 150 µg o.d. in combination with tiotropium 18 µg o.d. versus tiotropium 18 µg o.d. with respect to standardized area under the curve (AUC) for forced expiratory volume in 1 second (FEV1) between 5 min *…
To test the effects of a short psychological intwervention on quality of life, exercise capacity, self-management and health care utilisation.
To determin the effect of low dose azithromycin ( 3 times a week 250 mg) on the cough related health status in patients with COPD and chronic productive cough.In a randomized controlled study.
To assess the effect of low dose doxycycline on markers of neutrophilic inflammation and proteolytic activity stable GOLD III COPD patients.
Analyze the protective effect of fluticasone furoate, through reduction of allergic rhinitis, against exercise induced airway obstruction.
The objective of this study is to evaluate effects of the use of the Pelican instrument in routine medical care for asthmatic children in primary and secondary care.
To reduce the consumption of oral corticosteroids (OCS) in patients with severe asthma while maintaining asthma control, in order to decrease the incidence of long-term steroid-induced side effects and to improve quality of life (QoL). The specific…
Primary ObjectiveTo evaluate the efficacy and safety/tolerability of UK-432,097 DPI in adults with moderate to severe COPD (GOLD stage II/III).
In this study we will examine whether inhaled salmeterol inhibits house dust mite allergen-induced lung inflammation in mild asthmatics that are on maintenance treatment with low dose inhaled corticosteroids. If so, salmeterol may prove useful as…
2.1.1 Primary Objective:To evaluate the difference in the rates of graded pulmonary exacerbations in patients with bronchiectasis treated with inhaled mannitol compared with placebo control2.1.2 Secondary Objectives:EfficacyTo evaluate the…
The aim of this research is through feedback to increase physical activity of the patient and get a better distribution of activities over the day.
Primary: Efficacy of FF/GW642444 100/25 mcg once daily in comparison with that of FP/salmeterol 250/50 mcg twice daily during 24 weeks.Secundary: Safety and tolerability.
The aim of the study is to improve the clinical care and QoL for patients with COPD. We want to do this by means of the evaluation of the efficacy of pulmonary rehabilitation on cognitive function, mood, anxiety, and QoL in people with COPD. In…
1. To improve patient's quality of life in a cost-effective way by a self-management programme guided by doctors and a specialist asthma nurse through information and communication technology. 2. To investigate whether a simple index of asthma…
To assess indacaterol (300 and 600 ug once daily via SDDPI) superiority in patients with COPD as compared to placebo with respect to 24 h post dose (through) FEV1 after 12 weeks of treatment.
The purpose of this study is to determine the efficacy of an outpatient clinical care on demand in the management of COPD.
The aim of the study is to investigate the effects of a structured lifestyle program (in the first, second and third echelon) on the physical activity level of COPD patients
Primary Objective: To investigate the effect of supplementation of a single high dose of vitamin D (400.000 IU) on 1. the percentage of neutrophils in induced sputum, in non-atopic asthmatic patients with neutrophilic airway inflammation (…