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The peripheral effects of prednisolone on glucose metabolism, metabolic hormones, insulin sensitivity and insulin secretion in healthy young males and males with metabolic syndrome * two randomized, placebo controlled, double blind, dose-response, parallel group intervention studies.

The objective of these studies is to identify the primary mechanisms of GC-induced dysmetabolic effects in humans and to find biomarkers that reflect these side effects of GC treatment and which can be followed during therapy and in future clinical…

Perioperative urinary output and course of diuresis during outpatient treatment under general anesthesia.

Main question:Does a restrictive fluid management during general anesthesia lead to less urinary production?Sub questions:Does a fluid management with colloid fluid during general anesthesia lead to a change in urinary production?Does a different…