62 results
To gain further insight into the interaction and possibly shared pathophysiological mechanisms of female-specific cardiovascular risk factors and events we will quantify white matter hyperintensities on brain MRI and assess endothelial function in…
This study has two main objectives. One objective is to investigate which cognitive and affective mechanisms can be influenced through treatment which leads to improved social functioning. We will use a carefully selected set of behavioral,…
The primary objective of our study is to determine the efficacy and safety of top-down IFX treatment in moderate-to-severe pediatric CD.Secundary objectives are determination of PK data and predictors of response to IFX in pediatric CD.
The primary objective is to study the course of muscle (fiber) atrophy in elderly males and females with a fall-related hip fracture or elective hip surgery and the influence of additional nutritional support during hospital admission. Secondary…
To investigate the effect of tourniquet application on the coagulation system in patients undergoing a knee arthroscopy. A finding of more prominent activation of the coagulation system with tourniquet use than with non-use will create an important…
This study has two main objectives. The first objective is to investigate whether children with DBD, when compared to low aggressive and antisocial control children, have neuropsychological and neurobiological abnormalities that may underlie their…
To study the effectiveness of vitamin B12 supplementation on decreasing fatigue in IBD and IBS patients with increased or severe fatigue and normal vitamin B12 levels.
The primary objective of this experiment is to describe via an observational study the relation between conditions of sitting/standing up versus laying down in terms of bladder sensation in both volunteers and patients with OAB. We also want to…
To investigate whether the in vivo postprandial muscle protein synthetic response is augmented when dietary nitrate ingestion precedes protein ingestion in elderly type 2 diabetics.
Primary Objective: To study stimulating effects of prolonged (8h) enteral L-citrulline supplementation on the normalisation of the Arginine-NO metabolism.Secondary Objective: To study stimulating effects of prolonged (8h) enteral L-citrulline…
The objective of the study is to reveal the neurocognitive mechanisms by which mindful eating training acts. Moreover, the 1-year follow-up analysis will enable the comparison of mindful eating training with educational nutritional health methods on…
(A) Determine the influence of anger and frustration on self-reported bruxism.(B) Validation of a new ambulant electromyographic (EMG) diagnostic device for bruxism (TeleBrux).(C) Determine the additional value of peripheral modulation with…
Primary objective:• To investigate whether physical exercise prior to pregnancy in formerly preeclamptic women results in a comparable improvement of vascular and endothelial functioning as in women who had an uneventful pregnancy.Secondary…
The main objective of the present study is to test 1) whether paranoid anxiety moderates the relation between rejection and aggression, and 2) whether social anxiety moderates the relation between rejection and withdrawn behavior.
1. Randomised controlled determination of the influence of foods on the behaviour of a heterogeneous not-selected group primary school children, during the first two months of the trial. 2. Determination of an IgG or IgE-mediated respons to foods,…
The objective of this study is to evaluate a new and less invasive method of PGS. The new PGS technique will analyse a nucleus of a blastomere that was obtained by nuclear extraction rather than by biopsy of a whole blastomere.
The aim of the present study is to establish intero-interoceptive fear conditioning in healthy participants in a differential conditioning paradigm. We want to make use of *real* interoceptive conditioned stimuli: a low respiratory load and small…
This study aims to define the role of the IEC in S. aureus colonisation.
There is no long term prospective clinical research based on the principle of direct loading (within 24 hours) of overdentures on 2 implants with a bar in the mandible. Recently, for the period of 12 months, a pilot study has been carried out…
To compare the effectiveness of CBT versus IPT in the prevention of future relapse among residually depressed patients who received initial treatment. Our research questions: Are CBT and IPT following initial treatment effective interventions that…