16 results
To assess the impact of the combined ingestion of whey and collagen protein on myofibrillar and connective tissue protein synthesis rates in muscle tissue obtained at rest and during recovery from exercise in vivo in humans.
1) To determine if the 24 hour admission with TM can be omitted safely in the setting of CER for patients with low- and intermediate risk syncope (non-inferiority) 2) to determine the health care cost reduction (superiority), 3) additional…
In this study, we aim to prove a double dissociation between the contribution of dopamine and norepinephrine during the acute stress response.
The aim of this experiment is to determine the differential effects of noradrenaline and cortisol on memory accuracy versus generalization and to investigate the divergent effects of these stress mediators on the neural mechanisms underlying the…
The primary objective of the study is to demonstrate the specific involvement of the cerebellum in reversal learning. The secondary objective is to investigate whether the behavioural effects of cerebellar cTBS on reversal learning are moderated by…
Assess amyloid beta clearance from CSF to serum in response to HFCWO in healthy volunteers:- Change from baseline in amyloid beta 40 (ng/ml) in CSFAssess endogenous protein biomarker clearance from CSF to serum in response to HFCWO in healthy…
The aim of this experiment is to investigate whether training reappraisal will prevent stress-induced impairments in effective emotion regulation, and if this training effect is associated with reduced negative effects of acute stress on PFC…
The primary objective of this study is to investigate whether increases in brain dopamine enhance novel meaning inference in language processing, and what cognitive and neural mechanisms underlie this. We will test the hypothesis that dopamine…
The aim of this study is to investigate the effect of 12-week of 250 mg/day of olive leaf extract (OLE) supplementation on body composition and muscle strength, skin-aging and menopause-related quality of life in post-menopausal women (45-70 y).
The aim of this research proposal is to examine the effect of different ISIs on mTc-MEPs.Primary research question: What is the effect of different interstimulus intervals (ISIs) on mTc-MEP thresholds, peak-to-peak amplitudes, and area under the…
The primary objective of the PROTECT IV Trial is to demonstrate the superiority of percutaneous coronary intervention (PCI) performed with Impella® mechanical circulatory support (MCS; Impella CP®, Impella CP® with SmartAssist® or Impella 2.5®…
To implement pre-emptive panel based PGx testing in the LUMC and determine patient benefit of PGx guided drug prescription and dispensing.
In this study we will compare a hybrid DEB strategy with a conventional bailout 2-stent strategy (TAP/T-stenting or Culotte) in patients with a bifurcation lesion with sub-optimal side-branch result. The primary endpoint will be the composite…
The main objective is to investigate the effect of oral tributyrin on plasma endotoxin in patients with acute pancreatitis.
The aim of the EXACT@Home study is to further improve the assessment of treatable traits in patients with difficult to treat to severe asthma using ehealth before considering treatment with biologics.
The primary objective is to assess whether dual mobility cups reduce the risk of dislocations in patients with a femoral neck fracture treated with a THA by 50% within one year, as suggested by observational data.