19 results
The current project aims first to examine whether IPT produces outcomes that are superior to the comprehensive treatments already available ('care as usual'). Primary outcomes include parenting behavior and the quality of the parent-child…
Primary Objective: To investigate the effect of treatment with nebulized rhDNase on pulmonary function in children with asthma and persistent obstructive pulmonary function.Secondary Objectives: To investigate the effect of treatment with nebulized…
Impact of introduction of real-time viral PCR on clinical decision making and costs in children with a respiratory tract infection.
To establish: 1) the effectiveness of adenoidectomy compared to a non-surgical strategy in children in terms of reduction of upper respiratory tract infections (with or without fever) and improvement in quality of life 2) the costs-effectiveness of…
The objective is to investigate wether a brief CBT with parental involvement among children and adolescents with ASD reduces the risk of PTSD compared to a waitlist control group.
1. Development of a prevention strategy for CD in children from high risk families for the disease by induction of oral tolerance to gluten;2. Identification of the immunological mechanisms involved in initiating the aberrant response to gluten…
Objectives. The goals of the current protocol is therefore the natural follow-up of the objectives achieved with the previous grants and, in particular, of projects designed to discern new models for the successful conduct of clinical trials in…
Both in emergency departments and in prehospital services (ambulances and MMTs) effort is being done to find a fast alternative for the screw-tipped bone needle that has the least amount of risk and complications.The aim of this study is to analyse…
To evaluate the efficacy of inhaled rhDNase in addition to conventional treatment in children with an atelectasis during mechanical ventilation.
This study is designed to demonstrate superiority of efficacy of Propiverine hydrochloride compared to placebo in children suffering from overactive bladder with urinary incontinence.The primary objective is to compare efficacy of Propiverine…
Objective: to determine whether botulinum toxin A (btA) injections, intensive bimanual skill training, or a combination of both leads to more and better use of the affected arm in hemiparetic children in play, leisure time, school and personal care.
AimTo determine whether the prophylactic use of IVIg reduces the need for ET in neonates with Rh-D hemolytic disease.
To prove the efficacy and safety of ethanol lock solution in preventing catheter-related infections and subsequently venous thrombosis in children with a malignant disease who will have a tunnelled central venous catheter inserted.
To asses the effect of intermittent bolus nasogastric milk feeding versus semi-continuous milk feeding in preterm infants
During the course of the study 2 randomisation questions will be adressed. Both questions concern patients in the high risk group.Randomisation question 1: Will the addition of Doxorubicin to the first 4 standard IVA chemotherapy courses lead to a…
We hypothesize that cognitive behavioural family intervention will be more effective compared to standard treatment in regard to the perception of FAP and resolution of co morbid internalizing psychopathology.
Primary:To evaluate the efficacy of 0.2 mg/kg/day of clopidogrel versus placebo for the reduction of all-cause mortality and shunt-related morbidity in neonates or infants with cyanotic congenital heart disease palliated with a systemic-to-pulmonary…
To study the effect of a vitamin K-containing food supplement on osteocalcin carboxylation in healthy children between 6 and 10 years of age in the Netherlands.
Aim. The general aim of the study is to determine if cosmetic outcome will improve by applying silicone bandages to the wound. Cosmetic outcome is analyzed by size, colour, and surface of the scar. In addition it will be evaluated whether the…