16 results
The aim of this study is to explore the incidence of MTX related gastro-intestinal in a large cohort of JIA patients. Secondly, we want to investigate the effect of psychological behavioural therapy or switch to parenteral MTX dosing to ameliorate…
The aim of the project is to further develop and study the effectiveness of the Internet groupcourse Gripop Je Dip Online for young people (16-25 years) with depressive symptoms.Development objective:The eight-session groupcourse will be adapted…
The purpose of this study is to determine the effects of a strength training program on physical functioning in children with CP.
Determine the influence of methylphenidate treatment on sleep-wake rhythm and endogenous melatonin rhythm.
The main parameter of the study is evaluation and effectiveness of the treatment program on Body Mass Index (BMI) (as defined by Cole et al) compared to a standard intervention (increased physical activity and nutrient advice). Also the…
Dividing the study population in four categories (oncological patients, critically ill patients admitted to intensive care, neonates and other children) answers to the following questions are sought:- which initial dosage regimen for vancomycin…
The aim of this study is determine the efficacy and safety of Metformin as a weight reducing drug in the euglykemic, obese paediatric population.
The goal of this study is to determine whether a short course of amoxicillin/clavulanic acid reduces the number of urinary tract infections in children that have been catheterized during a short period.
Primary Objective: To investigate the effect of treatment with nebulized rhDNase targeted to the peripheral airways compared to rhDNase targeted to the central airways on FEF75 in children with CF who are on maintenance treatment with rhDNase.…
Aim of the study is to develop and test a brief intervention for adolescents who have to be treated in the emergency department of a hospital due to excessive alcohol use.
Primary Objective:To evaluate the efficacy of Oxabact TM to reduce urinary oxalate levels from Baseline to Week 24 in subjects with Primary Hyperoxaluria (PH).Secondary Objectives:To evaluate:* Percentage of subjects who have 20% or greater…
To study the effects and costs of the total individual CBT package and one of the components of the total CBT treatment package (i.e. mindfulness training) in a group format compared to Treatment-as-Usual (TAU) on the short and long term.
To characterize the multiple-dose pharmacokinetics of varenicline in adolescent maleand female smoking subjects
One of the recommendations of NICE for future research is comparing the effects of various psychological treatments for depression in youths. In particular, there is a need for studies in which parents are involved in the treatment (Birmaher et al…
1. To determine the efficacy of web-based CBT for adolescents with CFS;2. To determine which factors contribute to this efficacy;
To evaluate the cost-effectiveness of the Demands and Capacities Model based treatment (Dutch standard) compared to the Lidcombe programme for early stuttering intervention.Follow-up: Long-term outcome, taking into account recent genetic findings.