285 results
To assess the benefits and harms of two targets of partial pressure of oxygen in arterial blood (PaO2) in guiding the oxygen administration in acutely ill adults with hypoxaemic respiratory failure at ICU admission.
The main objective of this study is to investigate the effect of cerebellar tDCS on impulsivity in healthy adults.
As there are limited data on how to improve outcomes for those patients who do not benefit sufficiently from the availabletreatments, this study aims to compare MBCT to TAU as an adjunctive treatment to reduce depressive symptoms in patientswith…
This trial will prospectively test the use of ultrasound imaging and pleural fluid analysis in improving the management of patients with malignant pleural effusion.Primary objective: Establish if the use of TUS before and during the first 24-72…
(1) To compare adenoma miss rates (AMR) between Endocuff Vision-assisted colonoscopy (EAC) and conventionalcolonoscopy (CC)(2) To compare adenoma detection rates (ADR) between EAC and CC(3) To assess whether a proposed increased ADR and reduced AMR…
The randomized controlled trial (RCT) will be performed at Karakter Child and Adolescent*s Psychiatric Hospital and will be implemented at all locations, spread out over three provinces in The Netherlands. The project aims:1. To explore the…
To assess the provoking effect of partial sleep deprivation on paroxysmal neurological events in a EMU setting, in people with possible epileptic seizures.
Primary Objectives: * To determine if NA patients have altered cerebral activity related to motor planning of their affected arm compared to healthy controls and compared to their non-affected arm.* To determine if specific rehabilitation focused on…
The aim of this project is to assess the effectiveness of the Untire app in reducing Cancer Related Fatigue (CRF) and improving Quality of Life (QoL) in (former) cancer patients. It further aims to identify the parts of the app that are the…
To investigate whether perturbation of the left middle temporal gyrus results in immediate adaptation in the right hemisphere, indexed by a shift of alpha-beta oscillatory effects from the left to the right hemisphere.
Patient education on extended anticoagulation pros and cons: a journey app in venous thromboembolism
Our hypothesis is that patients whom receive targeted information about VTE and (extended) anticoagulation treatment with the 'patient journey app' on a daily basis in the week preceding their hospital visit will be more satisfied with the…
PRP injections are efficacious for symptom reduction and functional improvement compared to placebo injections in the treatment of ankle (talocrural) OA.
We hypothesize that MTX and LEF combination therapy is superior to MTX monotherapy in patients with psoriatic arthritis
• To evaluate the safety and tolerability of three oral dose levels of LTI-291 following 28 days of LTI-291 treatment in patients with Parkinson’s Disease with GBA-PD. • To characterize the plasma and CSF pharmacokinetics (PK) of LTI-291 following…
the foreign language training boosts cognitive flexibility and affects its neural underpinnings, which adds to cognitive reserve. The increase in cognitive flexibility is hypothesized to influence the experience of subjective cognitive decline.…
Antibiotics are over-prescribed for lower respiratory tract infection (LRTI) in nursing home (NH) residents due to diagnostic uncertainty. Inappropriate antibiotic use is undesirable both on patient level, considering their exposure to side-effects…
It is hypothesized that an online mindful parenting training for mothers with a toddler will be an effective intervention that will help in improving parental stress. It is additionally hypothesized that the online mindful parenting training is a…
It is hypothesized that physical activity will have a positive (dose-response) effect on cognitive control, measured as error processing, response inhibition and interference effect.
Hypotheses are that the program will have a positive effect on the health, safety, talent development and socioeconomic health inequities of youth and children in experimental neighborhoods in comparison to control neighborhoods.
Childhood obesity is a serious epidemic in western societies. Parents are considered as a key influence in children’s weight-related behaviors. It is thus not surprising that recent interventions to prevent childhood obesity have increasingly…