714 results
Patients with obesity face many health issues such as obstructive sleep apnea (OSA). Prevalence of OSA may be as high as 70% in high-risk populations such as morbidly obese patients undergoing bariatric surgery. Although bariatric surgery itself has…
We hypothesize that MTX and LEF combination therapy is superior to MTX monotherapy in patients with psoriatic arthritis
Knee OA is characterized by the presence of crepitus (knee sounds). Therefore, this device is able to record these sounds, while the subject is doing a knee movement, and screen for the presence or absence of osteoarthritis.
The hypothesis is that the 'Shine!' intervention will result in parents having better parenting skills and a higher self-efficacy to twice daily brush their children’s teeth, resulting in better oral hygiene and less dental caries…
The hypothesis states that the time tom complete an emergency airway with Cricath device is significant faster than with Quicktrach device, which will be studied on porcine cadaver models. In the second outcome, the hypothesis states that there is…
To investigate whether myocardial blood volume (MBV) is reduced in patients with non-obstructive coronary artery disease and signs and symptoms of ischemia, relative to healthy controls. The specific aims are to investigate 1) if MBV is reduced in…
1) Online treatment for nightmares is more effective than a wait-list control group. 2) Efficacy of online treatment is mediated by 'nightmare mastery'
The main objective of this study is to investigate which communicative strategies are most effective in increasing understanding and decreasing emotional impact in communicating increased risk for developing dementia status to persons with mild…
The primary hypothesis is that playing the serious game 'You & I' will be associated with an improvement of the mentalizing abilities in adults with mild to borderline intellectual disabilities. The secondary hypothesis is that…
Poor glycaemic control, indicated by an elevated HbA1c, is correlated to poor postoperative outcome in patients with diabetes mellitus undergoing surgery. However, improving glycaemic control before surgery has not been extensively studied so far.…
If there is a correlation between liking by smelling and liking by vaping, future experiments on e-liquid flavors would require smelling experiments only.
• To evaluate the safety and tolerability of three oral dose levels of LTI-291 following 28 days of LTI-291 treatment in patients with Parkinson’s Disease with GBA-PD. • To characterize the plasma and CSF pharmacokinetics (PK) of LTI-291 following…
In the proposed study we will investigate the effect
Pre-hospital triage in patients with low risk of NSTE-ACS will reveal a large saving in health care resources in favor of the pre-hospital rule strategy with additional GP management. At 12 months the strategy will corroborate with a very low event…
We hypothesize that transient inflammation/infection-associated deep venous thrombosis has a similar recurrence risk as 'classic' provoked deep venous thrombosis.
Validity: 1.) Correlation between total score of the questions about the construct "function" from the GNAKPS10-16 and the PSK in a group of 10-17 year old children with Osgood-Schlatter is equal to or higher than 0.70 with a p-…
1. The level of adherence to the prostate cancer surveillance guideline will not differ significantly between GP-led and specialist-led survivorship care. 2. GP-led survivorship care will be more cost-effective than specialist-led survivorship care…
To determine the presence or absence of central sensitisation in patients with Chronic Low Back Pain with radiation to the leg (CLBPr) and to determine the effect of segmental nerve interventions on central sensitisation.
the foreign language training boosts cognitive flexibility and affects its neural underpinnings, which adds to cognitive reserve. The increase in cognitive flexibility is hypothesized to influence the experience of subjective cognitive decline.…
We hypothesize that the subpopulation of CD68+Tie2+ macrophages is increased in diabetic patients in comparison to non-diabetic individuals. These macrophages may cause an increased expression of Ang2 in plaques, thereby enhancing angiogenesis which…