435 results
1. Mapping the effects of pain education on pain perception and psychosocial functioning of patients with CRPS.2. Further optimize the quality of care for patients with CRPS by further exploring the possibilities of a pain education program.
To assess the feasibility of a tailored eHealth intervention (primary) for cardiac patients with a low socio-economic position and explore its effect on patient activation, certainty and guidance (secondary) compared to usual care.
Primary Objective:What is the effect of a four-weeks combined TENS and exercise program, in comparison with no training, an exercise program or TENS only program, on the walking capability, perceived walking disability, and sense of fatigue of pwMS.…
To demonstrate that Plerixafor is able to reduce the need for invasive mechanical ventilation or death in severe COVID-19 patients admitted in Intensive Care Unit (ICU)
The objectives of the BREHAB pilot study include both process and research objectives. Analysis of the process objectives will enable the feasibility of a larger RCT to be assessed. They focus on the feasibility of prehabilitation and…
This study has been transitioned to CTIS with ID 2024-517387-37-00 check the CTIS register for the current data. The proposed multi-center population-based open-label randomized controlled trial with blinded outcome assessment will examine if…
This study has been transitioned to CTIS with ID 2023-505836-36-00 check the CTIS register for the current data. Main Objective:To demonstrate the superiority of galcanezumab versus placebo in the prevention of migraine in (at least) 1 of the…
Lifestyle intervention programs reduce inflammatory activity and might, therefore, be of added value in the management of patients with an inflammatory arthritis. Therefore, the aims of this randomized controlled trial are: 1. To compare the…
What is the clinical- and cost-effectiveness of early low-dose oral immunotherapy aimed at long-term tolerance induction in children under the age of 30 months with an established food allergy compared to routine care?What is the effect of early low…
Evaluate the antitumor activity of nemvaleukin alfa (*nemvaleukin*, ALKS 4230) in combination with pembrolizumab as compared with chemotherapy in patients with platinum-resistant ovarian cancerSecondary Objectives:Evaluate the antitumor activity of…
Primary objective: The primary objective of the study is to evaluate the clinical efficacy of ISIS 721744 in patients with hereditary angioedema (HAE).Secondary objective: Evaluate the effects of ISIS 721744 on the quality and pattern of HAE attacks…
Main Objective:To evaluate the efficacy of REN001 in subjects with PMM treated for 24 weeks, assessed by the effect on exercise endurance.Secondary Objective:To evaluate the efficacy of REN001 in subjects with PMM treated for 24 weeks, assessed by…
Primary Objective:1. To evaluate the efficacy of sonelokimab at 2 different dose levels (120 mg, 240 mg) compared with placebo in the treatment of participants withactive moderate to severe hidradenitis suppurativa.Secondary Objectives:1. To…
We hypothesize that using the Evotouch/7stascope, ultrasound guided TFEI procedures are non-inferior to the golden standard with fluoroscopy, which means correct placement of the needle within the neuroforamen without intravascular positioning.
The objective of this study is to investigate the effect of VR on post-operative pain and anxiety management in cardiac surgery patients undergoing a coronary artery bypass grafting (CABG) procedure.
The general aim is to identify the relevance and feasibility of a cost-effectiveness study on exercise therapy in patients with early stage knee OA1. What is the feasibility, in terms of percentage of eligible patients recruited, for GPs to recruit…
Prior to large trial, we will conduct a pilot trial comparing compare arthroscopic capsuloligamentous repair vs. coracoid transfer (Latarjet procedure) on recurrent dislocation rates and functional outcomes over a 24-month period.Primary questionsWe…
Primary Objective:To assess the effect of a 12-week moderate-vigorous intensity exercise intervention in fatigued IBD patients with quiescent disease on fatigue and health-related quality of life (HRQoL) (short term, measured at 3 months).Secondary…
The primary objective is to evaluate health related quality of life (HRQoL) after total hip arthroplasty using the DSA compared to the golden standard (PLA) in patients with incapacitating hip osteoarthritis after two weeks. The secondary objectives…
This study has been transitioned to CTIS with ID 2024-515480-66-01 check the CTIS register for the current data. To attenuate the impact and duration of delayed graft funtion by dampening schemia reperfusion injury