29 results
Documentation of the patients' functional recovery and quantification of fusion after implantation of 3-D trabecular titanium cages on the short and long term. These data will be compared with the recently performed randomized CASCADE trial on…
Primary Objective: To assess whether both OCT (optical coherence tomography) and/or HSI (hyperspectral imaging) detect differences in glioma tissue as compared to healthy tissue as examined during brain-surgery.Secondary Objective(s): To assess if…
The main objective is to investigate if the sensation of children with an upper OBPL is diminished. Both children that were treated conservatively as children that were surgically treated with nerve surgery in early infancy.The primary research…
The objective of this study is to examine the vestibular system in three dimensions. To achieve this goal three experiments are performed. The EyeSeeCam video-oculography is validated with the scleral search coils (international golden standard).…
primary objective:-to define the optimal glucose intake by quantifying endogenous glucose production and fractional gluconeogenesis in critically ill children.secundary objectives:-determine glucose utilization in relation with exogenous glucose…
Safety and performance will be based on a comparison of overall success rates of the Barricaid ARDand either a concurrent group (nonrandomized) of control patients treated by conventional surgicalmethods (e.g., noninstrumented discectomy) at select…
1. To implant a functional vestibular prosthesis using the ampullar *V*-approach, as developed in our own clinic.2. To investigate protocols for adjusting the vestibular implant (VI) to required settings, regarding:-- Modulation sensitivity--…
Our objective is to obtain insight into whether and how the visual and auditory systems of hemispherectomized patients have adapted after brain damage and brain surgery in early life. For this purpose we will perform psychophysical tests and (…
1. To study safety, feasibility and technical effectiveness of minimally-invasive endoscopy-guided surgery for treatment of supratentorial ICH; 2. To estimate the potential effect of minimally-invasive endoscopy-guided surgery on functional outcome…
Deep Brain Stimulation in Patients with Chronic Treatment Refractory Anorexia Nervosa: a Pilot Study
The aims of this research project are:1) to establish the efficacy and feasibility of DBS as a last resort treatment in patients with chronic, treatment refractory AN. 2) to associate the efficacy and functional effects of DBS in patients with…
The primary objective of this study is to quantify the reduction in lumbar pain in a GelStix* treatment group compared with a control group receiving a saline solution injection as placebo.The secondary objectives are to assess: 1. the impact of…
It is required to compare results from conservative- and surgical treatment in The Netherlands and to perform an economic evaluation in order to evaluate the cost-effectivity of both treatment types. On one hand, surgical treatment seems accompanied…
Main objectives:- Investigating the relation between language functioning and resting-state EEG characteristics in brain tumour patients.- Predicting language outcome after brain tumour surgery, on the basis of pre-operative EEG characteristics.…
The goal of this prospective cohort study is to assess fracture union/stability and clinical outcome after surgical and conservative treatments of type II/III odontoid fractures in the elderly patient (>=55 years). The general presumption is…
To evaluate Multiple Independent Current Control (MICC) perception and sub-perception based programming at Dorsal Column (DC) targets and Dorsal Root (DR) targets for focal foot, knee, or groin pain relief.
The objective of the study is to clinically assess the safety and effectiveness of LIQOSEAL® as a means of reducing intra- as well as post-operative CSF leakage in patients undergoing elective cranial intradural surgery with a dural closure…
To compare the (cost-)effectiveness of early surgical hematoma evacuation versus a conservative treatment in elderly patients with a traumatic ASDH.
In this non-inferiority trial, we aim to demonstrate that 3D-printed guides are just as good as CAS, regarding the postsurgical radiological screw-insertion accuracy.
Primary Objective: To optimize the current DBS-treatment of advanced PD. For the primary objective the following research questions will be answered: By performing STN DBS under general anesthesia, will there be a significant reduction in cognitive…
The primary objective is to determine the limited-efficacy of both the experimental systems in comparison to our previous cohort that was treated with the more traditional MCGR. Limited-efficacy will be determined in terms of maintenance of the…