7 results
To investigate whether the upregulation of CK16 and Ki-67 (a marker for cell proliferation) in the FPSU is specific for HS, measured in inflammatory nodules and pseudo-comedones, in comparison to other dermatologic conditions that have comparable (…
To assess the effect of Caphosol® oral rinse on clinical outcomes of selected oral symptom burden (oral mucositis/stomatitis (aphthous-like), oral pain, taste change (dysgeusia), difficulty swallowing (dysphagia), difficulty oral intake, and dry…
To describe the composition of the BMZ along the interfollicular and follicular epidermis of perilesional HS skin and to investigate whether the expression of these proteins differs from normal skin of healthy control patients. Additionally, a…
Therefore the primary objective of this study is to evaluate the effect of twice daily application of topical clindamycin1%/benzoyl peroxide 5% gel compared with the standard treatment with topical clindamycin1% lotion on the frequency of active…
The primary objective of this prospective study is to assess the clinical efficacy of the combination of adalimumab and surgery compared to adalimumab monotherapy after one year of treatment in adult patients with moderate to severe HS at the last…
To compare the microbiome, histology, immunohistochemistry and gene expression profile of healthy skin from the axillae or groin of 10 healthy volunteers with uninvolved axilla or groin skin from age, gender, body mass index, and smoking status…
The primary objective of this trial is to assess the long-term safety of spesolimab in patients with HS who have completed the 1368-0052 PoCC trial and are qualified for entry into this trial. The secondary objectives are to evaluate efficacy at a…