Search for a trial

Anorectal function and the effect of childbirth in patients with M Crohn

Disease activity, perianal involvement and lesion localisation are important influential parameters making sure no pregnancy is exactly alike and mode of delivery needs to be considered on an individual patient level.A complete anorectal function…

Obstetric anal sphincter injury, a follow-up study on the long term outcome.

Aim of the study is to get informed on the outcome of women treated in the MUMC for obstetric anal sphincter injury between 2005 and 2012. The controlgroup is matched for maternal age at delivery, parity, mode of delivery and child weigth.

pelvic floor physiothearpy in treatment of anal fissure (PAF-study)

The effect of pelvic floor physiotherapy with biofeedback in patients with anal fissure and pelvic floor dysfunction.

Brain activation in fecal storage, defecation and fecal incontinence: an fMRI study in healthy volunteers, fecal incontinent patients and sacral neuromodulation

The purpose of the present study is the identification of brain areas and patterns involved in the sensory process of fecal urgency, and how these areas and patterns are influenced by sacral neuromodulation. We hypothesize that fecal incontinent…

Role of host cell DNA methylation analysis in predicting non-regression or regression of high-grade anal intraepithelial neoplasia in HIV+ men trial (MARINE)

In this study we clinically validate if host cell DNA methylation markers can predict (non-)regression of HGAIN, thus determining the need of immediate treatment versus active surveillance and the safety of withholding treatment. This could prevent…