22 results
Primary objectives:1. What is the effect of walking on a treadmill compared to walking in a patient-in-charge mode on kinematics in healthy subjects?2. What is the effect of walking on a treadmill compared to walking in a patient-in-charge mode on…
The objective of this feasibility study is compare the smart AFO + standardized shoes to subjects* own AFO + own shoes. Subjects* experiences with the orthotic devices will be evaluated and points for improvement will be asked. Subjects* performance…
To determine the effect of botulinum toxin type A injections in stroke patients with stiff knee gait.
The main objective of this study is to investigate the effect of a single tDCS session in children with mild CP on different motor tasks. The second objective is to identify the optimal site of stimulation. In tDCS research the electrodes can be…
In this study the effect of SAS and the treatment with CPAP on cognitive functioning, fatigue and mood in stroke patients will be investigated. The main research questions are: 1) Is there a relationship between (the severity of) SAS and cognitive…
Overall objective:The overall objective is to test the hypothesis that GLP-1 receptor activation of CNS reward and satiety circuits occurs, in the context of food(-related) stimuli, and that this effect is altered in individuals with obesity and…
The main objective of this study is to examine the effect of different kinds of augmented feedback on learning an arm motor task.
The aim of the study is to measure whether there is a difference in LDL cholesterol levels or the 24 hour ambulatory blood pressure in individuals at high risk of cardiovascular disease when the polypill is taken in the morning compared with the…
The primary aim of the trial is to assess what the optimal treatment regimen for acetylsalicylic acid, a statin and two BP-lowering agents is (administered as in regular care in individual agents, a fixed-dose combination pill administered in the…
The primary objective is to assess the effect of tDCS using different electrode configurations on corticomotor excitability in the lower extremities of chronic stroke survivors and healthy subjects. Secondary objectives are (a) to assess the effect…
Identify the effect of tDCS parameters on motor learning in healthy individuals by measuring effects on visuomotor adaptation rate and retention, and study the influence of a common BDNF mutation.
The purpose of this study is to investigate the acute effects of a single bout of WBV on spasticity of calf muscle in stroke patients.
The objective of this study is to examine the influence of a single dose of fluoxetine and of movement observation on cortical activity, and to relate the changes of the activity of the brain to muscle activation, motor function and motor control in…
- What are the effects of different types of ankle foot orthoses on weight-bearing and static and dynamic balance contribution of the paretic and non-paretic leg in stroke patients? - What are the effects of different types of ankle foot orthoses on…
The objective of this study is twofold.One aim of the study is to investigate the effects of tDCS (anodal, cathodal and sham) on balance correcting responses and simple reaction times in lower extremity muscles. We will determine whether the effects…
Primary objective: To acquire motor maps of the BR and the MD muscles by using the pseudorandom walk method and assess their change after long-term motor learning. Secondary objectives: Compute muscle synergies from the motor maps and assess their…
Primary objective:To test the hypothesis that the calcium channel blocker amlodipine has a superior beneficial effect on cerebrovascular reactivity in patients with symptomatic SVDs when compared to either the Angiotensin II type 1 (AT1) receptor…
To investigate if conventional tDCS can be improved by using a new electrode configuration. To find a relation between ongoing EEG and MEP magnitude. To investigate the effect of tDCS on cortical excitability (measured with TMS), brain activity (…
To explore the effect of single versus repeated preconditioning on circulating blood factors (i.e. metabolomics analysis) as a likely mechanism in patients with cSVD. Secondly, we explore whether the effects of single versus repeated preconditioning…
Delayed cerebral ischemia (DCI) is an important cause of death and dependence after SAH. Vasospasm plays an important role in the pathogenesis of DCI, because many patients have constricted arteries during the period of DCI, but vasospasm is not a…