609 results
To test whether a short FD protocol can be used to test whether effects of light on alertness, sleep, metabolism and temperature are under circadian control.
The primary objective of this study is to investigate the acute effects of a Breinspijs meal on the cognitive domains attention, processing speed, working memory and episodic memory. Secondary objectives are the effects of a Breinspijs meal on…
Primary aim: To determine the effects of oro-sensory exposure stimulation through mastication duration and sweetness intensity on the endocrine and metabolic cephalic phase responses.Secundary aim: To determine whether the magnitude of cephalic…
The present project characterizes the use of 15N-intrinsically-labelled milk protein as a reference-protein for development a minimal invasive method that can be used to assess protein quality in human subjects. For this purpose, our primary…
The primary objective of this study is to compare the acute effects of single doses of methadone (5 and 10 mg) and buprenorphine (0.2 and 0.4 mg) with placebo on driving performance and cognition. Secondary objective is to study the pharmacokinetics…
The objective of the proposed experiments is to study the effect of lighting intensity and spectral composition (correlated colour temperature) on thermal comfort and thermo physiology. The obtained insights can be used to improve thermal comfort,…
The primary objective of this study is to determine the independent and additive effects of oro-sensory exposure (mastication effort) and ingestion rate (bite interval) on satiation in relation to the cephalic endocrine and metabolic hormonal…
To investigate the effect of modafinil (200 mg) and caffeine (300 mg) on vigilance in low, medium and high caffeine consumers during the circadian trough in order to determine the best pharmacological agent to target fatigue.
Primary Objective: to assess the immediate and delayed effects of THC on true and false memories in a legal context (i.e., on eyewitness and offender statements).Secondary Objective(s): to link drug-induced false memory effects to…
- To evaluate the pharmacokinetic (PK) profile of the combination of GLPG3067, GLPG2222, and GLPG2737 following repeated morning versus evening doses given to healthy female subjects - To evaluate the safety and tolerability of the combination of…
The objective of this study is to investigate the extent of respiratory depression at equi-analgesic dosages of tapentadol and oxycodone
Investigate if an increased consumption of VITACEL Wheat Fiber can enhance fecal bulk. Furthermore, we want to demonstrate that the increased consumption of wheat fiber can increase stool frequency and consistency.
Our goal is to manufacture a 3D-IOD which is designed digitally, and subsequently 3D-printed. Such 3D-IOD, can be made cheaper, faster and more patient friendly. To prove such a statement, patients should at least be even satisfied about their 3D-…
Primary Objective: To study the differences between EB post oxygen-dive, post air-dive (control), dry-dive (recompression chamber) and pre-dive (baseline).1. Will an exposure to a PO2 of 190 kPa (100% oxygen at 9 msw) during 60 minutes in an…
We hypothesize that formerly pre-eclamptic women have persistently increased angiotensin II sensitivity, sodium sensitivity, insulin resistance and sympathetic nerve activity together initially leading to susceptibility for early renal disease and…
To compare the plasma amino acid responses after the digestion of a milk protein powder with varying levels of protein glycation in healthy young men.
The main objective of this study is to find if there is a measurable improvement of transfemoral amputees standing up with the active knee support prosthesis (ERK) in comparison to standing up without active knee support.
The primary objective is to assess the post-prandial serum amino-acid profile of duckweed protein in healthy adult volunteers in comparison to a another plant-based high-protein crop: green pea. A secondary objective is to assess post-prandial…
Hypotheses: - Ileal delivery of casein and/or sucrose induces stronger effects on satiation compared to placebo- Ileal delivery of casein induces stronger effects on satiation than ileal fat delivery- Ileal delivery of sucrose induces stronger…
The primary objective of this study is to assess the efficacy of Ecopipam to reduce self-injurious behaviors (SIB) in adults and children with Lesch-Nyhan Disease (LND) in an outpatient setting. The secondary objectives of this study are to assess…