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Cognitive and emotional effects of sleep apnea and its rehabilitation in stroke patients

In this study the effect of SAS and the treatment with CPAP on cognitive functioning, fatigue and mood in stroke patients will be investigated. The main research questions are: 1) Is there a relationship between (the severity of) SAS and cognitive…

Alternative APAP Method for Non-invasive Positive Airway Pressure Therapy in OSAHS patients.
Amendment: Mallampati score as a predictor for effective Positive Airway Pressure

1. To investigate whether an adjusted mode of APAP can improve patients adherence in comparison to fixed CPAP in present-day PAP therapy of OSAHS patients.2. To investigate the agreement between the parameters of the CPAP devices and the polygraphy…

Mannitol inhalations as a new procedure for testing of airways hyperresponsiveness

1. To test feasibility of mannitol inhalations in a Dutch pulmonary out-patient clinic.2. To compare time and costs involved in measuring airways hyperresponsiveness by methacholine to mannitol

Mannitol inhalations as a faster procedure for testing of airways hyperresponsiveness

1. To test feasibility of mannitol inhalations in a Dutch pulmonary out-patient clinic.2. To compare time and costs involved in measuring airways hyperresponsiveness by methacholine to mannitol

A Prospective, Randomized, Placebo-Controlled Multicenter Study to Evaluate the Performance of the IBV Valve System for the Treatment of Severe Emphysema

The objective of this randomized, blinded, multicenter, controlled study is to compare the performance of the IBV* Valve System (treatment group) to a control group receiving a sham bronchoscopy procedure without valve placement

Effect of Carbon Dioxide Enriched Ambient Air on Pharmacokinetics and Deposition In Bronchiectasis Patients Using Tobramycin Inhalation: A proof of concept study.

1. To asses (with planar imaging) whether SPECT/CT scan are feasible in assessing pulmonary deposition of inhaled tobramycin.2. To evaluate the effect of CO2 enriched ambient air on deposition of inhaled tobramycin in bronchiectasis patients.3. To…

A randomized cross-over trial in the effect of automated oxygen control devices on the distribution of oxygen saturation in preterm infants

To compare the effect of two automated oxygen controllers (Oxygenie and CLiO2) on time spent within oxygen target range in preterm infants.

Does Automated closed-loop ventilation Reduce the DRiving Pressure levels in patients with ARDS (AiRDRoP) - an international multi-center crossover study and randomized controlled trial

The objective of this crossover study and randomized controlled trial is to compare ΔP levels during INTELLiVENT®-ASV with conventional lung protective ventilation in patients with moderate or severe ARDS.

Does High Flow Nasal Cannula (HFNC) facilitate CO2-washout during EBUS under procedural sedation?

The objective is to investigate if there is a flow-dependent effect of HFNC on ventilation during an EBUS procedure under procedural sedation in patients with COPD gold class 3-4.

Optimising Oxygenation of Preterm infants during Respiratory support by fine-tuning Automatic TItration of Oxygen

To compare the effect of two target ranges (91%-95% and 92%-96%) while on automated oxygen control on the time spent under the target range in preterm infants.