15 results
Primary objective• To assess the effect of use of a walk-bike in IPF patients for 8 weeks on health-related quality of life, measured with the St. George Respiratory Questionnaire, at baseline, week 9 and week 18, in patients with IPF.Secondary…
Primary Objective: To study the differences between EB post oxygen-dive, post air-dive (control), dry-dive (recompression chamber) and pre-dive (baseline).1. Will an exposure to a PO2 of 190 kPa (100% oxygen at 9 msw) during 60 minutes in an…
To optimize ventilator support in critically ill patients admitted to the intensive care unit by monitoring electromyography of the respiratory muscles.
Primary: Assessment of the short-term effect of a Heat and Moisture Exchanger on tracheal mucociliary clearance in laryngectomized individuals. Secondary: The relationship between clinical assessment, ciliary activity and mucociliary clearance.
The aim of this study is to access the effect of low and high VT (ml/kg) on pulmonary and systemic inflammatory responses and the release of oxygen and nitrogen free radicals in the paediatric patient with and without ALI.
To investigate whether exposure to nanoparticles is able to induce short-term functional changes in the brain, we previously exposed human volunteers for one hour to diesel exhaust particulates (300 ug/m3) and followed their brain activity during…
With intervention with bronchodilators (usual care bronchodilators for COPD subjects), in one study histamine and in one study steroids, we want to investigate the respons on inspiratory lung function parameter like the FIV1 and also investigate…
Evaluate the effect of pediatric asthma eHealth care on the healthcare utilization, asthma outcomes and quality of life.
To compare MP under INTELLiVENT-adaptive support ventilation (ASV), a fully-automated closed-loop ventilation, with MP under conventional ventilation.
This study has two parts. The main objective of part 1 (in vivo) is todetermine changes in markers of oxidative stress in exhaled breath as a result of different short term oxygenation strategies (liberal versus conservative) . The main objective of…
By using advanced respiratory monitoring, we will aim to gain more understanding about the physiological effects and potential benefits of FCV in comparison to PCV in patients with moderate to severe ARDS. We hypothesize that FCV results in a lower…
Primary objective is to measure the effect of the use of different HMEs with different fluid exchange, and the effects of changing between HME routines, on the tracheal mucociliary transport in laryngectomered individuals.Secondary objectives are to…
Our objective with this proposal is to study the interaction between nintedanib and green tea capsules with > 60% ECGC in fibrotic ILD patients. Depending on the presence and magnitude of the interaction, we will be able to give practical…
Primary ObjectiveTo evaluate the efficacy of lumacaftor/ivacaftor combination therapy (LUM/IVA) in subjects with cystic fibrosis (CF) 12 years of age and older who have at least one A455E mutation.Other Objectives* To explore the association between…
The objective of this crossover study and randomized controlled trial is to compare ΔP levels during INTELLiVENT®-ASV with conventional lung protective ventilation in patients with moderate or severe ARDS.