26 results
PrimaryTo determine whether the palatability of a newly developed formulation of valacyclovir is non-inferior to administration of crushed and suspended tablets in children, is the primary objective of the second phase of the trial.The primary…
The primary objective is to investigate if there are differences in the acute postprandial vasodilating effect between different protein sources and if these differences are associated with differences in the responses of vasodilating factors.…
Study 1:- Determine whether loss aversion behaviour (i.e. increased sensitivity to losses compared to gains) is modulated by dopamine levels using a pharmacological challenge- Assess whether this effect is accompanied by the modulation of brain…
Primary Objective: to ascertain whether tVNS affect performance (as measured by modulation of reaction times and/or error rates) in two cognitive tasks designed to examine PES and PIA, as well as specific components of pupillary response that will…
The primary objective is to show that energy expenditure of the body, during moderate physical activity on a bike ergometer, can become higher in response to high altitude simulation. The secondary objetive is to show that an increase in energy…
Fundamental research with the objective to gain more insight in empathic processes within people suffering from psychopathy. Goal is to evaluate if affective empathic can be temporarily altered (in terms of minutes).
We aim to provide causal evidence for the following:Study arm one: That the oscillatory brain response produced by a visual stimulus can be modulated by tonically altering cortical excitability using tDCS.Study arm two: That functionally relevant…
Primary Objective: to ascertain whether administered clonidine and scopolamine affect performance (as measured by modulation of reaction times, learning and/or error rates) in a range of cognitive tasks designed to examine uncertainty estimation and…
The aim of the proposed study is to conduct an evaluation of the validity of web-based completion of the (Child-) ACT on the basis of comparison with paper-based completion and to test reproducibility of both web-based and paper-based version.…
The objective of this study is to investigate the effects of stimulation of noradrenaline and acetylcholine and the blockade of NMDA-receptors on neural and behavioral measures of perception and consciousness.
The specific mechanism of inhibition differs between SST variants, it remains the question why. Our envisaged study focuses on this question. We expect that the difference is caused by the amount of perceptual overlap between the go stimulus and the…
To assess the effect of enteral feeding with higher protein content compared to standard protein content on indicator amino acid oxidation in ICU patients.
By using advanced respiratory monitoring, we will aim to gain more understanding about the physiological effects and potential benefits of FCV in comparison to PCV in patients with moderate to severe ARDS. We hypothesize that FCV results in a lower…
In this research study we want to assess whether eating potato-rich food products are a good dietary strategy to recovery both liver and muscle glycogen stores following exhaustive exercise in healthy young endurance trained males over 24 hours.
The aim of the present study is to investigate the effect of a citrus extract rich in the flavonoids hesperidin and naringin on sleep quality and mental wellbeing in healthy subjects with sleep (minor) disturbance.
The purpose of this study is to examine the effect of exogenous ketone body supplementation on carbohydrate metabolism during exercise.
The primary objective of this study is to unravel the effects of dopamine D2 receptor stimulation on gating of working memory, reinforcement learning, and reward-based motivation, and their associated physiological changes (measured with fMRI and…
To investigate the impact of different doses of handgrip exercises (moderate vs high intensity) and stimuli (exercise vs ischemia) on the ability to protect endothelial damage from ischemia-reperfusion injury in healthy humans. A secondary goal is…
This study aims to answer the following questions: 1. Is there a difference in the time to onset of the first symptom between HH and NH?2. Is there a difference in the severity of symptoms between HH and NH?3. Is there a difference in the time to…
The primary objective is to evaluate if and to what extend replacing all meat products in an average Dutch diet with currently commercially available PBMAs affects the systolic blood pressure of middle aged men and women in a 2x8 week fully dietary…