45 results
1. Regular physical follow-up can partly be replaced by nurse-led telephone follow-up, with at least similar quality of life (QoL), in breast cancer patients treated with curative intent. ( change in QoL < 5 points) 2. An informative/…
An upfront RBCT aiming at low-normal Hb levels will ameliorate anemia-caused tumor hypoxia-related resistance to chemotherapy before the start of chemotherapy and may decrease secondary anemia-induced endogenous release of cytokines like VEGF,…
In the pathogenesis of medullary thyroid carcinoma a mutation of the RET thyrosine kinase system plays an essential role. In animal models the thyrosine kinase inhibitor imatinib showed tumor regression. So a Phase-2 study in patients with…
1. Comprehensive geriatric assessment has no benefits in selecting patients fit for chemotherapeutic treatment, compared to clinical judgement by the medical oncologist; 2. Observational report of the functional outcome of treating ovarian carcinoma…
In patients presenting with chest pain complaints and an intermediate risk of coronary artery disease, Multi-Slice Computed Tomography (MSCT) will have a higher specificity as compared to myocardial perfusion imaging (MPI). Accordingly, MSCT may…
There are predictive markers of treatment response (or non-response) at baseline or during early beginning of treatment?
The helical geometry of this vascular access prosthesis reduces flow stagnation and low shear stress at the venous anastomosis resulting in diminished neointimal hyperplasia.
1. Welke rokers hebben baat bij welke transmurale “stoppen-met- roken- interventiestrategie”?; 2. Wat zijn de effecten van de verschillende “stoppen-met- roken- interventiestrategieën”?
Speech understanding with a speech processor fitted using the parametric fitting procedure and the recipient's own fine-tuning is as good as with a conventional fitting. The parametric fitting is more patient friendly and less time-consuming.
One tailored letter on smoking cessation will lead to more quit attempts at follow-up.
Evaluation of efficacy and safety of two different formulas of alfa-Galactosidase A, agalsidase beta (FabrazymeTM) and agalsidase alpha (ReplagalTM) in an equal dose of 0,2 mg/kg in order to detect any differences between these two drugs.
Botulinum toxin A declines the severity of tardive dyskinisias.
A self-management program including self-treatment of exacerbations, leads to a reduction in the severity and duration of exacerbation compared to a similar self-management program without these self-treatment guidelines in hospital out-patients…
A two month distraction period results in similar clinical beneficial effects as a three month distraction period.
1. To develop (cost-) effective implementation strategies which are feasible in daily practice; 2. To test the guidelines in a multicentre effectiveness trial; 3. To develop general quality indicators with appropriate measuring tools for diagnostic…
Is diagnostic non-invasive coronary angiography with MS-CT a cost-effective alternative to diagnostic invasive coronary angiography in the management of patients with stable and unstable angina pectoris, referred for evaluation of the presence of…
1. The recognition of malnourished inpatients will improve by using the SNAQ malnutrition screening tool at admission; 2. Early recognition and treatment of malnutrition is effective and cost effective.
Tumor response from erlotinib and bevacizumab as first line treatment in advanced NSCLC will result in “non-progressive disease” within 6 weeks in more than 50% of patients.
Opening wedge HTO treated with DBM will better match one year post-operative mechanical axis alignement with pre-operative planned correction then opening wedeg HTO filled with autogenous iliac crest bone.
Long-term administration of Ibopamine hydrochloride eye drops restores and maintains intraocular pressure in patients with hypotony following vitreoretinal surgery for ablatio reinae, or uveitis.