18 results
We aim to i) describe flow patterns and flow-related dynamics in the ascending aorta of patients with aortic valve stenosis, ii) compare these flow parameters before and after surgical aortic valve replacement and iii) compare flow parameters with…
To gain a better insight into the genetic factors that play a role in the etiology of the thoracic aortic aneurysm with the following specific aims:1. Study of specific geneitc factos that play a role in the pathogenesis of both syndromic and non-…
1 Assessment whether using a nerve-sparing exposure of the aortoiliac tract during vascular reconstruction will lead to a neurophysiologically intact sympathetic pathway to the intra-pelvic organs and thus to an intact postoperative function.2…
The principal goal of this study is to identify whether and how innate immune host factors predispose to the development of chronic Q-fever.
The main goal of the current study is to gain insight in the development and rupture rate of aneurysms and to detect potential markers that predict the risk of aneurysm rupture.
1a) To determine the prevalence of digital pathology, possibly as a result of digital emboli, in the dominant hand in symptomatic and asymptomatic elite Dutch male volleyball players. 1b) To determine the association between the presence of digital…
1a) To determine the prevalence of anomalies of the PCHA in the dominant shoulder in symptomatic and asymptomatic elite male volleyball players. 1b) To determine the association between anomalies of the PCHA in the dominant shoulder with the…
1a) To determine the prevalence of anomalies of the PCHA in the dominant shoulder in symptomatic and asymptomatic elite male and female beach volleyball players. 1b) To determine the association between anomalies of the PCHA in the dominant shoulder…
The aim of the study described in this protocol is the identification of genes involved in aortic aneurysm development. This will be achieved by characterization of large AA families, including pedigree investigations, diagnostic measurements (…
To establish an operational reference database on intracranial aneurysms encompassing clinical and genetic data on at least 800 patients, 400 controls and 400 relatives of patients where a familial trait is recognized, together with imaging data on…
1. The application of 4D flow MR imaging to analyse blood flow patterns (flow angle, flow asymmetry), regional vessel wall parameters (regional wall shear stress, vessel wall thickness) and pulsed-wave velocity in neoaortic root, carotid artery and…
Our primary aim is to evaluate in clinical practice the predictive value of unruptured intracranial aneurysm wall enhancement for aneurysm growth. It will allow to set up a secure, efficient and personalized follow-up.
The research project focuses on identifying early predictors (brain damage, cognition and behavior) for recovery after a SAH. The research also focuses on using advanced neuro-imaging for better mapping of (indicators of) brain damage after a SAH,…
To determine whether reactive gliosis persists >3 years after SAH and whether this response relates to cognitive impairment after SAH.
The purpose of the pivotal study is to determine the safety and efficacy of IMPEDE-FX RapidFill for increasing the percentage of subjects with shrinkage of the abdominal aortic aneurysm sac when used as an adjunct to on-label EVAR stent graft…
Primary objective: To investigate if the presence of aneurysm wall enhancement predicts aneurysm instability in the long-term. Secondary objective: To investigate if the absence of aneurysm wall enhancement predicts aneurysm stability in the long…
The goal of this study is to investigate whether BOLD MRI can predict the occurrence of buttock claudication after coiling of the internal iliac arty. The BOLD technique will be used to measure blood supply parameters of the gluteal muscle during…
The main objective of this study is to find biomarkers for the prognosis of the BAV patients by investigating ECFC and EPC functioning, and to gain knowledge on physiological and pathological processes in patients by investigating molecular…