33 results
Is the BOLD MRI able to show the difference in the level of oxygenation as a mesurement of ischemia between a in a healthy kidney (<30% renal artery stenosis) and a kidney with more than 70% artery stenosis?
The primary objective of this study is to determine the anti-Xa activity after a reduced therapeutic dose of nadroparin in patients with an eGFR < 60 ml/min in comparison with the anti-Xa activity after a standard therapeutic dose of…
Primary Objective: • To compare urinary concentrating capacity in ADPKD patients with healthy subjects and patient with IgA- or membranous glumerulopathy.Secondary Objectives:• To compare urinary concentrating capacity in ADPKD patients with an eGFR…
To assess the long-term consequences of live kidney donation, regarding kidney function, survival, hypertension, diabetes, systolic and diastolic blood pressure, mental state and quality of life.
The overall aim of this study is to evaluate the use of the thrombin generation test in patients with CKD, including haemodialysis-dependent patients.
To evaluate the diagnostic performance of diffusion weighted MR imaging (MRI) techniques by using apparent diffusion coefficient (ADC) maps and Diffusion Tensor Imaging (DTI) on 3 tesla MRI in assessing the nature of renal masses.
to study the effect of everolimus (vs. mycophenolate) on dyslipidemia, ectopic fat accumulation, and cardiovascular function against a common calcineurin inhibitor (CNI) background.
Primary Objective: Our primary objective is to investigate the effect of NAC on H2S levels in plasma in different patient groups, i.e. healthy volunteers, CKD patients, and dialysis patients. We hypothesize that there is an increase in H2S levels…
Ascertain feasibility, study burden, between-subject and within-subject variability of automated RH-PAT measurements in paediatric renal transplant recipients. Comparison of adipokines and inflammatory profiles in renal transplant recipients and…
To study if there is a role for prophylactic VZV vaccination prior to transplantation to boost the patients B- and T-cell repertoire and thereby reducing the incidence and morbidity associated with herpes zoster.
To compare cerebral activity patterns during emotional and cognitive processing among depressed patients with CKD and patients with regular depression.
Primary: 1 to test the safety and feasibility of autologous MSC therapy in HLA-DR mismatched patients with SCR in the renal biopsy 4 weeks after renal transplantation.Secondary1 To assess histologic changes before and after MSC treatment.2 To…
Primary objective: To assess the degree of tacrolimus over-exposure in renal transplant patients with mild diarrhea while on treatment with tacrolimus and mycophenolate mofetil.Secondary objective: To assess the intra-individual variability of…
inventarisation of the interaction between furosemide and sevelamer
Assessment of microvascular alterations using orthogonal spectral polarization and correlate this with markers for endothelial cell dysfunction, fibrosis and histology in patients with renal function impairment who will undergo renal biopsy and…
With this pilot study we want to see if there are measurable differences in body composition after one year. In what way does the body composition of patients change during the first year after transition from CHD to NHHD or NCHD? Is the weight gain…
Objective of this study is the development of a national "best practice guideline on pre and postnatal follow up for prenatally detected abnormalities of the kidney and/or urinary tract". Furthermore, the guidelijne will be evaluated and…
Primary• To determine the safety profile of oral topotecan in subjects with cancer andmildly moderately or severely impaired renal function (Groups C, D and E) compared to subjects with cancerwhose renal function is normal and who have received…
1. To quantify and characterize BM progenitor cells in patients with CKD as compared to healthy controls. 2. To explore strategies to improve BM stem and progenitor cell function ex vivo.
This study assesses the effect of oral iron supplementation on gut-derived plasma uremic toxin levels in patients with chronic kidney disease (CKD) and with iron deficiency. The main research questions to be answered are:1. Does oral iron…