23 results
To determine if a marked change in the concentrations of one or more of the selected biomarker is evident before PUs are visible
Documentation of the patients' functional recovery and quantification of fusion after implantation of 3-D trabecular titanium cages on the short and long term. These data will be compared with the recently performed randomized CASCADE trial on…
The main objective is to investigate if the sensation of children with an upper OBPL is diminished. Both children that were treated conservatively as children that were surgically treated with nerve surgery in early infancy.The primary research…
The primary objective is to find out whether there is enhanced processing of sensory stimuli when people are in pain and to find out whether SCS has influence on the processing of sensory stimuli applied on non painful body parts. We focus on the…
The main objective is to examine the effectiveness, the costs and the cost-effectiveness of an integrated *fast track* rehabilitation service for multi-trauma patients (SFTRS) involving dedicated early rehab intervention programs. The SFTRS is…
Gain insight in the anatomy and organisation of the sacral plexus in children with NB and congenital spinal or sacral anomalies. Possible findings can be compared with the results of the healthy subjects, in order to be able to relate findings to…
Our main aim is to describe the 24-h circadian rhythm of skin and core body temperature in people with SCI and examine whether changes in melatonin and/or cortisol relate to the altered circadian rhythm in core body temperature recently described in…
The goal of this pilot study is to collect data about basal values and variations in these values of the damage markers FABP, Myoglobin, CK and CRP of people with a low complete spinal cord injury. This pilot study is a preparation for a large…
The primary objective of this study is to identify the brain changes following peripheral nerve injury and establishing their functional role in recovery. The secondary objective is to evaluate new fMRI methodology in a patient population.
The aim of the study is to develop and evaluate a specific client centred task-oriented training module for upper extremity skilled performance in persons with C-SCI.The research questions are:1. Does an 8-weeks client-centred task-oriented training…
The aim of this research is to examine the effects of changes in proprioceptive and visual information on balance control in WAD sufferers. Although clinical experience suggests more effective balance control due to elevated proprioceptive…
To visualize the affected nerve roots using DTI with tractography. The anatomy and organisation of the nerves on the level of the lumbar disc herniation will be visualized. Diffusion parameters as FA, ADC, AD, and RD could provide valuable…
To gain more insights in the mechanical properties of soft tissue under high risk for deep tissue injury type of pressure ulcers with US and MR Elastography.
The primary objective is to study the association between maternal TL and the risk of SB in offspring. The secondary objectives are to investigate the relation between maternal TL and obstetrical (pregnancy course and outcome), environmental risk…
Safety: To provide confirmatory evidence that use of the LIFT System, inclusive of all components and accessories, is safe.Effectiveness: To provide confirmatory evidence that use of the LIFT System provides an effective treatment for the…
The aim of the study is to determine the accuracy of pedicle screw placement when using the iNav navigation tool compared with the established computertomography based navigation.
To investigate if a personalized multimodal physical therapy program compared to ACDF surgical treatment is non-inferior over a 12-month period and cost-effective in patients with painful cervical radiculopathy who have an indication for…
The purpose of this post-approval protocol amendment is to extend the follow-up of subjects who were originally enrolled in theRCT, EUBARD-CP_001 protocol. This study extension will examine the long-term survivorship of the Barricaid® ACD when…
This project focuses on the characterization of the immune response following a traumatic SCI. As individual components of the immune response work in close collaboration and have a strong influence on each other, it is important to obtain a very…
Objective: The primary objective of this proposal is to develop new sensitive and quantitative outcome measures for clinical trials in LBSL. The secondary objective is to identify biomarkers to stratify patients based on disease progression rate.