53 results
COMT and/or PRODH polymorphisms are debt to cognitive deterioration in velocardiofacial syndrome.
Presence of postural instability and gait dissorder PIGD (gait disorders, balance impairment, falls, fal-related injuries and FOG) are an important and disabling feature of idiopathic Parkinson’s disease (PD) where the level of functional ability is…
In this observational trial we would like to study the possible correlation between the probe-drug dextromethrophan and tamoxifen pharmacokinetics. In case a good correlation is available, this might help in a stepwise development of truly…
The incidence of gastric cancer has been declining steadily since the 1930s, but it remains a major cause of cancer death in the Western world. The high mortality rate reflects the prevalence of advanced disease at presentation. The five-year…
Pregnancy rates will not differ between patients with a positive and negative result of the PCT.
The application of the haemostatic device, ACF-matrix haemostat will reduce blood and fluid loss from the LIMA bed after CABG surgery.
Cancer patients who develop thrombosis have a worse prognosis than cancer patinets without thrombosis. There is evidence that activation of the coagulation cascade increases tumor growth and angiogenesis. Therefore the objective is to find a marker…
The hypothesis to be tested is that treatment with three courses of R-DHAP + MTX combined with rituximab i.t., followed by ASCT is feasible and that the efficacy meets the expectations as described in the protocol.
Pre-operatieve training in oudere orthopedische patienten - een experimenteel en klinisch onderzoek.
Pre-operative training improves physical recovery after surgery for lumbar spinal stenosis.
The novel anti–tumor necrosis factor monoclonal antibody adalimumab was significantly superior to placebo for long-term treatment of CD irrespective of concomitant immunosuppressive therapies, including the thiopurines azathioprine (AZA) and 6-…
Duogestan® leidt in symptomatische, vroeg postmenopausale vrouwen tot een verbetering in kwaliteit van leven van 20%.
The current rise of CA-MRSA in the Netherlands is due to them all being MRSA of Unknown Origin (MUO). We do not know the risk factors yet of these. If we do, the CA-MRSA will drop.
The most severely ill patients have the poorest peripheral tissue perfusion and oxygenation, which will negatively influence the accuracy of continuous glucose monitoring measurements.
DYANA Study - Dynamic Annuloplasty System with Activation for the Treatment of Mitral Regurgitation.
To assess the safety and efficacy of the MiCardia Dynamic Annuloplasty System for the treatment of mitral regurgitation with optional intraoperative activation and optimization.
Our overall aim is to create a cost effective non-invasive method of pre-surgical assessment of language and memory function using MEG scanning. We propose a research project with the key objective to evaluate the effectiveness of a Dutch…
Multi-modality imaging can predict repsonse to systemic treatment in colorectal cancer.
It can be expected that the during the tasks with resistance, the movements are performed slower, less smooth and with less movement range. Also a larger amplitude in muscle activation can be expected. During the tasks with gravity compensation,…
Cytokine expression in lumbar disc tissues correlate with development of chronic neuropathic pain.
Improved detection of tumor.