110 results
Main objective: 1) To investigate whether BAT activity differs between South Asians and Caucasians.Secondary objectives: 1) To investigate whether sympatic stimulation of BAT differs between South Asians and Caucasians2) To investigate the…
Primary objectives:1. To determine image quality and diagnostic accuracy of CE-MRV using a new, optimized high resolution 3D T1 weighted volume interpolated gradient echo sequence with fat suppression (THRIVE) with both a blood pool and a…
To fully characterize skeletal muscle strength and endurance, phenotype and muscle fiber type-specific satellite cell content in frail elderly as compared to those elderly that do not classify as frail according to clinical criteria.
The main objective of this study is to detect potential biomarkers for the differentiation of PD and DLB and the differentiation of PD subtypes by using neuroimaging.
1) Evaluating the effect and recovery of glioma surgery in eloquent areas on cognitive functioning.2) Examining the effec tof glioma surgery in eloquent areas on quality of life.3) Examining the effect of gliomas in eloquent areas on the…
The aim of our project is in-depth characterization of the microbiota components both adjacent to and within the mucosa in patients with IBD, by applying novel high-throughput analysis technology in a global description strategy approach.…
The aim of this study is to create a prognostic model enabling the clinician to predict the outcome of a septic episode. Furthermore, by getting more insight in the pathophysiologic proces of sepsis, we could discover new possible targets for future…
Identifying translational EEG endophenotypes in mice and man that will determine cross-species genetic findings on behavioural and cognitive traits, including psychiatric disorders.
To determine the effect of hypoglycaemia on BAT-activity.
In the proposed project we aim to predict falls in daily life and to identify both aging- and disease-related impairments that underlie impaired postural control and an increased risk of falling in daily life.
The primary objective is to gain insight into the causative mechanisms of exertional dyspnea in HFPEF. We hypothesize that exercise induced pulmonary hypertension plays a significant role in the development of complaints. The secondary objectives…
Main objective: Perform a genome wide association analysis on remission of asthma in a cohort of subjects who were previously diagnosed as having asthma. Secondary objective: Perform genetic association studies between asthma remission and (pathways…
Ascertain feasibility, study burden, between-subject and within-subject variability of automated RH-PAT measurements in paediatric renal transplant recipients. Comparison of adipokines and inflammatory profiles in renal transplant recipients and…
Previous studies [10] have proposed that cartilage degeneration due to obesity could be caused by changes in the joint kinematics during ADL that shifts the loading applied to cartilage. Such a shift may cause regions of cartilage to become newly (…
To measure the 18F-fluoride activity of otosclerosis in patients diagnosed with otosclerosis (by audiometry, CT scan and/or operative findings) in a different stage of their disease. If this diagnostic proves to be reliable and reproducible, this…
With the experimental set-up of this study we would like to address the three following objectives:* Investigate HRV baseline levels in individuals with pre-clinical arthritis, healthy subjects and active RA, to evaluate if pre-clinical arthritis…
Analysis of volatile organic compounds in exhaled air as a non-invasive biomarker for liver diseases
To identify VOC profiles in exhaled air that are unique for specific liver diseases.
Subproject 1: To investigate the neurophysiological correlates of implicit and explicit selective attention to alcohol cues and emotional cues in alcohol-dependent patients compared to healthy controls Subproject 2: To investigate whether it is…
To study in clinically stable COPD patients with muscle atrophy eligible for out-patient pulmonary rehabilitation:1.The short-term effects of 4 months exercise training including nutritional supplementation versus exercise training alone on physical…
Primary Objective: *To study differences in pulmonary function (i.e. increased airway resistance) one year after hospitalisation for RSV LRTD between mechanically ventilated and non-ventilated infantsSecondary Objectives: *To study…