52 results
Primary Objectives:- Determine the effect of pulmonary vasodilatation on indexed cardiac output during simulated exercise.- Characterization of structural properties of small pulmonary arteries.Secondary Objectives: - Investigate the effect of…
Since October 2010 the Catharina-hospital in Eindhoven offers a cardiac rehabilitation program to cardiovascular patients. As an optional section of the program an adjusted training of MBSR is offered, called *stress reduction in cardiovascular…
The aim of this study is to assess differences between lean and morbidly obese subjects in gut permeability, gut microbiota and mucosal inflammation and to assess the effects of weight loss after sleeve gastrectomy on gut permeability, microbiota…
The identification of axial SpA in the primary-care setting and the introduction of questionnaires that could optimize the pattern of referral to secondary care is one of the most important objectives of the CAFASPA-II study.
Primary Objective: To determine T cell response to Coxiella burnetii antigens using an ELISPOT interferon gamma release assay in patients with different clinical outcomes after acute Q fever
To obtain insight in the role of the innate immune response, especially Type 1 interferons, in the pathogenesis of RSV LRTI. New techniques are used to unravel the local (nasopharyngeal) immunological milieu during viral LRTI. The hypothesis is that…
To predict the risk of particular coronary plaques to cause myocardial infarction
The aim of the present study is a performance evaluation of INNOVANCE® PFA P2Y. The first objective is the determination of a reference interval for the Intended Use Population (patients eligible for Clopidogrel therapy). This will be done by…
To investigate if endoscopic transgastric necrosectomy will lead to a reduction ofthe per- and postoperative pro-inflammatory response, as compared to necrosectomy by laparotomy, in patients with infected (peri-)pancreatic necrosis.
The main question in the study isHow do moderately preterm infants and their parents differ from term, as well as extreme preterm infants in (a) development and self regulation skills of the infants, (b) interaction patterns and relationship between…
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The primary goal of this research is to characterize the regulatory Treg population in peripheral blood and bronchoalveolar lavage in patients with sarcoidosis compared to healthy controls. What is the frequency of these cells, what is the phenetype…
The main objectives are :Cross-sectional:1. To investigate the extent of atherosclerotic disease of the carotid artery defined as: (a) the intima-media thickness (IMT) (b) the elasticity (c) the degree of stenosis2. To define the degree of…
Determination of possible risk factors for developing osteoporosis in GOLD II COPD patients.
The main objective of this study is to analyse the effect of fetal sex on levels of T and macrophage cell subsets in decidual tissue. Secondary objectives will be to analyse differences in the effect of maternal blood stimulation by fetal leukocytes…
Using electroencephalography to relate behavioural research on Autism Spectrum Disorder (ASD) to electrophysiological findings.
Better knowledge and awareness of Late Effects after pediatric HSCT for non-malignant diseases will lead to optimal screening procedures after HSCT that may eventually contribute to reduce transplant-related long term morbidity and mortality and…
Objective: As we have to integrate information on genetics, immune cells and microbes, a panel of biomaterials (isolated from blood, stool and gastrointestinal mucosal biopsies) will be sampled. From these samples genomic, transcriptomic,…
• Characterization of methylation patterns in blood samples and finding of methylation patterns that are unique to lung cancer.• Development of a molecular test for early diagnosis of lung cancer from a blood sample that will be more sensitive and…