6725 results
The main point of this study is to detect in a controlled fashion if there is a relationship between CCSVI and MS. We focus on 5 parameters indicative of CCSVI: 1-reflux in the internal jugular vein (IJV) or in the vertebral vein (VV), or both with…
Understanding the pathophysiological mechanisms that play a role in liver cirrhosis and its complications. For that aim, we want to study the functional and morphological intestinal epithelial barrier and microbiota of both small and large intestine…
Main objective: 1) To investigate whether BAT activity differs between South Asians and Caucasians.Secondary objectives: 1) To investigate whether sympatic stimulation of BAT differs between South Asians and Caucasians2) To investigate the…
W want to investigate the influence of a mutaion in the MH allel on the HPV and the normal reaction of MH patients to hypoxia
PrimaryTo investigate the inter-rater and intra-rater variability of a novel neurophysiological measurement (Motor Unit Number Index, MUNIX) for estimation of functioning motor units, in healthy controls and ALS patientsSecondaryTo evaluate the…
The main aim of this research is to search for sensitive and specific QEEG markers to differentiate between children with a developmental disorder, in this case ADHD and ASD, and a control group and to differentiate between these two developmental…
Primary objectives:1. To determine image quality and diagnostic accuracy of CE-MRV using a new, optimized high resolution 3D T1 weighted volume interpolated gradient echo sequence with fat suppression (THRIVE) with both a blood pool and a…
To fully characterize skeletal muscle strength and endurance, phenotype and muscle fiber type-specific satellite cell content in frail elderly as compared to those elderly that do not classify as frail according to clinical criteria.
Primary Objective: To determine whether topical application of Calcitriol (Silkis) 3 µg/g, Diclofenac 10% or a combination of both can lead to a 40% histological reduction (*)/increase (*) of expression of the following antibodies: Ki67 (*), BCL2…
The objective is to investigate the effects of a combined strength and aerobic exercise program on cognition, physical functioning, social functioning and ADL.
Primary Objective: The primary goal of this research project is to evaluate the effect of a rockered shoe on walking and running biomechanics in healthy athletes and athletes with Achilles tendinopathy. The reason for using a patient group is that…
Determine whether feedback by means of motivational gaming can (partially) restore cognition-related deviations in motor performance as seen in back challenging conditions in CLBP patients.
The primary objective of this study is to investigate the effect of - short vs. long - oro-sensory exposure combined with a gastric load - low vs. high in energy -, on gastric emptying rate. As secondary outcome we want to investigate the effect of…
The aim of the study is to test the hypothesis that susceptibility to and severity of certain infectious and inflammatory diseases can be explained by the interaction between the genome, microbiome and immunological responses: i.e. presence of…
Primary objective: - To study the pharmacokinetics of acetaminophen and metabolites in morbidly obese patients and compare with normal weight patients. Secondary objectives: - To compare the pharmacokinetics of acetaminophen and metabolites in…
The objective of the current proposal is to further explore the pathophysiological changes that occur in patient with an IGSF1 mutation, using an established method for assessing hormone secretory characteristics.
To objectify the effect of the VLS-system during daily use regarding postural stability and quality of life.
to find evidence for frontal inhibition during planning of explicit movements just as seen in patients with conversion disorders.
1. To establish whether serial exhaled breath analysis using eNose can detect invasive pulmonary aspergillosis in patients with prolonged chemotherapy induced neutropenia (neutrophil counts <0.5 x 10^9 for more than 7 days).2. To establish…
The main objective of this study is to detect potential biomarkers for the differentiation of PD and DLB and the differentiation of PD subtypes by using neuroimaging.