9 results
The goal of this research project comprises two important components that are intricately related:1) To define the pathophysiological state of the peripheral motor pathway in patients with SMA and to determine the contribution of the constituting…
Identify if dexamethasone treatment alters the frequency and functionality of atypic B cells in blood.
This study is set up 1) to validate the Young Schema Questionnaire (YSQ) and Schema Mode Inventory (SMI) aimed to explore early maladaptive schemas and schema modes underlying personality functioning, and 2) to explore schema activation related to…
To assess the uniqueness of diabetic cardiomyopathy (DCM) relative to other forms of cardiomyopathy using unsupervised clustering approaches based on deep phenotyping (clinical, imaging and biological) information. With the results of this study we…
To improve our understanding on the etiology of proximal DVTs, to identify risk factors for stent reinterventions and to optimize treatment after a venous stent. To improve patient education and expectation after a venous stent.
Primary Objective: • To determine the prevalence of NHR and BHR and determine the relationship between them in patients with chronic allergic and non-allergic rhinitis and compare with controls.Secondary Objective(s): • To determine differences in…
The role of glutamate and GABA in cognition in subjects with chromosome 22q11.2 copy number variants
The main objective of this study is to investigate the role of glutamate and GABA in cognition in healthy subjects with 22q11.2 CNVs and healthy subjects without 22q11.2 CNVs using high-field Magnetic Resonance Spectroscopy (MRS). Additionally, we…
To study the safety and efficacy of prolonged (>2 hours) end-ischemic DHOPE, by assessing the occurrence of (serious) adverse events during machine perfusion and within 30 days after liver transplantation.
Primary Objective- To identify (a combined set of) clinical and non-clinical markers most sensitive to disease progression in Dutch SCA1 mutation carriers. Secondary Objectives:- To quantify the annual change in disease-relevant clinical scales and…