341 results
Study on the validity and usability of myBLOxs portbale centrifuge at home by patient with heartfailure. Validity is measured by comparing laboratory results from venous plasma with those from capillary plasma.
Primary Objective: comparing hemodynamic stability provided by titration of esmolol in addition to standard perioperative care including low-dose metoprolol to placebo and standard care.Secondary Objective(s): -comparing the incidence of…
-Determination of the effects of an exercise program on ectopic fat accumulation in heart, liver and skeletal muscle-To assess the relationship between metabolic and inflammatory parameters with changes in MRI outcome-To assess the differences in…
The aim of this study is to identify direct markers of muscle and adipose tissue hypoxia in COPD and CHF patients in relation to the altered muscle oxidative phenotype and the putative mediators HIF-1α and PPARs/PGC-1. Insight in the underlying…
1. To evaluate the clinical usefulness of STIC with post-process rendering capability. Our goal is to investigate whether STIC gives more accurate information about a suspected cardiac anomaly, compared to conventional 2D ultracardiography.2. To…
The aim of this clinical study is to determine, what the effect of RBC transfusion is on the microcirculation after cardiac surgery in the ICU, as compare to asanguineous colloid (Gelofusine®) infusion.
Our primary objective is to measurec glycocalyx volume with OPS imaging, before and after sublingual nitroglycerine-spray administration, in patients with premature atherosclerotic disease before the age of 40 years and a positiev family history for…
Aim is to establish the relation between plasma and tissue AGE levels and the severity of diastolic/vascular dysfunction and its relation with symptoms in patients with type 2 DM with and without CHF, and in patients with CHF without DM. Primary…
Routine evaluation of dyssynchrony in pediatric patients with cardiac disease is feasible using standard and novel echocardiographic techniques. The extent of cardiac dyssynchrony and its influence on cardiac function differs between groups of…
To investigate whether IC administration of abciximab during primary PCI is superior to IV administration in improving myocardial perfusion in patients with STEMI.
1. To investigate the causal relationships between atherosclerotic disease risk and existing, long-term cyanotic heart disease. 2. To differentiate these causal relationships according to each of the assessed risk factors and their relationship with…
This study is focused on determination of risk factors associated with preeclampsia and intrauterine growth restriction, both develop in early pregnancy. These pregnancy complications are associated with cardiovascular diseases in later life. We…
- To determine physical fitness in children with a congenital heart disease (ventricular septum defect, atrium septum defect, tetralogy of Fallot, transposition of large arteries and patients after a (modified) Fontan-operation) and to compare…
The study aims at examining the effect of an individual tailored lifestyle intervention to reduce the cardiovascular disease risk in people with FH.Secundary, the study aims at promoting a healthy lifestyle (no smoking, proper nutritional pattern,…
To investigate the genetic, genomic and proteomic basis of hypertension and susceptibility to hypertension-related target-organ damage (renal insufficiency and heart failure).
To investigate the relation between premature cardiovascular disease and glycocalyx perturbation
1) To asses heparin-induced LPL release curves in patients with the Mets 2) To determine differences in gene expression of LPL, GPIHB1 and ANGPTL4 in muscle and adipose tissue of patients with the MetS compared to health controls3) To determine…
To observe the possible relationship between central, conventional hemodynamic parameters with relatively new peripheral, regional perfusion parameters in two versions of a model with controlled vasocontriction (cooling) - vasodilation (heating)
To study whether microcirculatory perfusion is improved by ECMO. Perfusion will be studied before & after ECMO start, during ECMO weaning and before & after ECMO stop. To study the precictive value of perfusion and its correlation…