41 results
Primary Objective: To show that an integrated chronic care program in a specialized AF clinic reduces cardiovascular hospitalizations and mortality.Secondary Objective(s): 1) To demonstrate the benefits of an integrated chronic care program in terms…
We aim to i) characterize flow patterns and ii) assess energetic properties in the LV of patients with LBBB (with and without heart failure) and iii) compare findings with those in healthy volunteers.
Main objective is to compare the incidence of subclavian vein thromboses after TLE by manual traction alone versus TLE with use of the mechanical rotational dilator sheath in case of fibrous adhesions hampering extraction by manual traction alone.…
To assess whether atrial flow patterns during sinus rhythm in patients with atrial fibrillation differ from healthy controls with sinus rhythm.
The primary objective of the RAPID study is to determine whether etripamil nasal spray (NS) self-administered by patients is superior to placebo at terminating episodes of PSVT in an at-home setting.The secondary objective of this study is to…
Primary objective: Our primary objective is to investigate whether niagen normalizes blood-based energy metabolites, mitochondrial levels and proteostasis levels. Secondary objective: To examine whether niagen reduces AF burden in patients with…
Main objectiveTo identify and describe the electrophysiological substrate and triggers in patients with (an increased risk of) VTAs using ECGI, in order to improve understanding of arrhythmic mechanisms and use these for arrhythmia risk…
The primary objective of this study is to investigate if a smart technology intervention could improve prognostic factors in patients who underwent cardiovascular surgery, more specifically earlier identification of adverse events such as sternal…
The objectives of this study are: 1) to assess the feasibility, accuracy and efficacy of simultaneous, conventional and micro-electrode mapping using the QDOT catheter to delineate and ablate the functional substrate of post-MI VT compared to…
The primary objective will be evaluating the difference in detection of new AF between the intervention practices (yearly 7 days AF screening with continuous heart rhythm monitoring) and control practices (care as usual) over three years of follow-…
to quantify atrial electropathology of the endocardium in adult patients with CHD and to correlate clinical characteristics, atrial volume, electropathology, atrial ectopy and features of pre- and post-procedural atrial fibrillation.
The primary objective of this study is to detect HRV patterns which are related to cardiovasculair disease such as permanent atrial fibrillation or (congestive) heart failure using a wearable fitness tracker.
To elucidate the correlation between proteostasis marker levels in serum and atrial tissue, and initiation and progression of AF in patients.
The aim of this study is to investigate to what extent biomarkers are related to the development of ventricular arrhythmias, in order to improve the indication for ICD therapy.
- Enrolment of a representative cross-section of AF patients in Europe.- Detailed analysis of clinical and relevant parameters (digitalised ECG, cardiac imaging, blood biomarkers) that could be used during clinical practise for the diagnosis of…
Primary objectives: The first aim is to examine the role of microtubule network in electrical conduction, protein localization and function in induced cardiomyocytes from pediatric BrS patients, life threatening ventricular arrhythmia patients and…
The main aim of this study is to improve knowledge on the hemodynamic burden of labour in women with cardiac disease and women without cardiac disease, by examining CO trajectory through the full course of labour. Therefore, we specified the…
To identify arrhythmogenic electromechanical risk profiles in LQTS patients; in baseline conditions and during provocation; the recognition of risk profiles will improve risk stratification for sudden cardiac death.
Evaluate the effect of the menstrual cycle on QTc among females with LQT1 or LQT2 and to put our previous findings in a broader perspective by including controls groups and older females.
Primary Objective: To noninvasively obtain arrhythmogenic substrate mapping using ECGI in patients with polymorphic VT and/or idiopathic VF.Secondary Objectives: - To detect similar arrhythmogenic substrates in index patients of family cohorts with…