11 results
We aim to gain insight into the incidence and severity of CIPN and its influence on patient-reported outcomes (i.e. health related quality of life (HRQoL), disease-specific complaints, depression, fatigue, sleep problems) among a prospective…
1) To investigate what changes are present in skeletal muscle tissue of elderly gastric and colonic cancer patients (>80) compared with younger gastric and colonic cancer patients (<60) and compared to elderly controls and younger…
Primary objective of this study is the identification of familial germline mutations in SPS. Secondary objectives are to get a better insight in the molecular pathway of SPS and associated colorectal carcinoma, to discriminate those family members…
To investigate whether local inflammation in the area of the stomach and gastroenteric anastomosis is a cause of primary DGE.
Is is possible to detect tumorcells in blood in patients with colon cancer with RT-q-PCR.
To determine which DC populations are present in esophageal tissue of patients with reflux esophagitis and BE. Relate the findings regarding DC populations to other pre-malignant gastrointestinal disorders (IBD).
Primary objective:To determine the relative risk of gastric cancer for genetic polymorphisms.Secondary objectives:- To determine the relative risk of gastric cancer for combinations of genetic polymorphisms, H. pylori virulence factors and lifestyle…
Primary Objectives:1. To compare protein synthesis rate of the tumour and normal pancreas between cachectic and non-cachectic patients with pancreatic cancer.Secondary Objective(s):1. To compare protein synthesis rate of liver, intestinal, adipose…
The primary aim of this study is to describe the relationship of I/R injury during hepatic resection and hepatic microcirculation. The hypothesis is that the microcirculatory alterations concerning the total vessel density (TVD), microvascular flow…
AimThe MAPS study aims to unravel the immune composition of the human peritoneal cavity and the tumor immune environment in peritoneal metastasized gastric and colorectal cancer. The overarching aim is to find new targets for immunotherapy for this…
Western Management strategies have been ineffective to modify the poor prognosis of GC. This proposal will focus on this specific challenge to *improve GC outcomes*, and will seek to gather evidence through international high-quality translational…