36 results
The current study aims to investigate the effect of a) caloric restriction (very low calorie diet (VLCD)); b) caloric restriction with mechanical restriction and physiological changes through malapsorption (Roux- en- Y bypass (RYGB) surgery); and c…
To demonstrate differences in neuronal structure and neuronal function in brain regions that control eating behaviour between obese and normal weight adolescents.
We propose that there will be a link between taste sensitivity and overall metabolic function. We hypothesize that non-tasters, medium-tasters and super-tasters will have different levels of metabolic hormones in their general circulation. Our study…
The aim of this study is to assess differences between lean and morbidly obese subjects in gut permeability, gut microbiota and mucosal inflammation and to assess the effects of weight loss after sleeve gastrectomy on gut permeability, microbiota…
The objective is to describe the nature and underlying (neuromuscular en biomechanical) factors of dysphagia in different neuromuscular diseases in relation to different consistencies of food. Identifying the contributing factors are starting points…
Primary objective:To observe the effect of gastric bypass surgery on household members and partners who live together with the patient on body mass index (measured as weight/height²) in the first year following bariatric surgery compared to family…
Primary Objective: To study the effect of VNS on BAT activity.Secondary Objective(s): Measure the effect of VNS on energy expenditure, core temperature, skin surface temperature and skin perfusion during active and absent stimulation.Follow the…
This study aims to evaluate the efficacy of an extensive eSupported lifestyle program in reducing physical risk factors.
The primary goal of the proposed study is to investigate striatal D2R levels and eating behavior before and after dopamine depletion in order to build knowledge on the interactions between the brain reward system and overeating behaviour. This will…
The aim of the study is first to develop knowledge concerning underlying mechanisms that can explain the relationship between obesity and asthma.
To determine 1) the differences in the effects of food stimuli on the activation of brain regions associated with energy homeostasis and reward between women with chronic AN, women recovered from AN and healthy normal-weight women, 2) the…
We propose that variation in genes involved in the regulation of motivational behaviour and satiety plays a major role in the development of obesity. We aim to identify these genes using family-based association and linkage analysis in a large…
With this pilot study we want to see if there are measurable differences in body composition after one year. In what way does the body composition of patients change during the first year after transition from CHD to NHHD or NCHD? Is the weight gain…
The primary objective of the study is to determine which questions are most predictive for undernutrition in hospitalized children in order to develop a quick and easy screening tool that is valid, reproducible and suitable for the population of…
The objective of this study is to test the hypothesis that healthy obese pregnant women at increased risk for obesity-related pregnancy complications can be identified by a subgroup-specific screening program at twelve weeks amenorrhea.
We propose that variation in genes involved in the regulation of motivational behaviour and satiety plays a major role in the development of obesity. We aim to identify these genes using family-based association and linkage analysis in a large…
Objective 1To describe the course and underlying mechanisms of dysphagia in children with congenital myopathy (from 6 months to 12 years)Objective 2To formulate recommendations for early detection, diagnostic assessment , treatment and advices for…
The main objective of this study is to investigate whether changes in nutritional status correlate to changes in frailty status, and whether these changes impact on disability as a clinical outcome in patients with chronic obstructive pulmonary…
The objective of the study is to determine hypothalamic function in response to oral glucose ingestion in obese subjects.
Primary Objective: The primary objective of this study is to investigate the prevalence EPI in the advanced HF population Secondary Objectives: • To determine the association between exocrine pancreatic function and markers of HF• To determine the…