44 results
Primary aims:1. To perform a population-based screen to estimate the exact frequency ot transient leukemia in Dutch newborns with Down syndrome2. To investigate the realtionship between transient leukemia and the occurrence of DS ML and ALL at later…
This study-protocol is directed at the comparison of two accepted management strategies at both ends of the current treatment-spectrum of moderate hypoglycemia in 'high risk' newborns: an intensive treatment versus an expectant monitoring…
To prove that 1 corticosteroids administration is the main factor in diminished bone density of preterm neonates, 2 dexamethasone has more influence than hydrocortisone and 3 children with abberant ricketsscreening have a transient diminished bone…
To determine the rate of transmission of prilocaine across the placentaTo determine the levels of methemoglobinemia in newborns after perineal block with prilocaine during labor (following the regimen used in our hospital)To determine the levels of…
The primary objective of the study is to examine muscle atrophy in fetuses with single or bilateral IPEV, in comparison to a normal population by measuring the circumference of the upper and lower legs by ultrasound examination. The length of the…
The quality and quantity of the innate immune response to bacteria should be tightly regulated leading to resolution of infection while minimizing damage to host tissue. We hypothesize that this regulation depends on gestational age at delivery and…
To explore cardiovascular remodelling with subsequent altered cardiac function (assessed as strain rate) in extremely premature neonates (born <30 weeks and/or birth weight < 1000 gram) with FGR.
The primary objective is to study the association between maternal TL and the risk of SB in offspring. The secondary objectives are to investigate the relation between maternal TL and obstetrical (pregnancy course and outcome), environmental risk…
To evaluate the effect of FICare in SFR on cognitive development at 5.5 years of age as measured by the WPPSI-IV in preterm infants hospitalised in a level-2 Neonatal Ward as compared to SNC in OBU To evaluate the effect of FICare in SFR on parental…
In 2004, a multidisciplinary team of clinicians and researchers in the UZ Leuven hospital started to collaborate on the rare problem of cancer during pregnancy. The collaboration between gynaecologists, pediatricians, hematologists, farmacologists,…
The aim of this study is to evaluate the diagnostic value of sCD14-ST in the diagnosis of neonatal sepsis. The secondary aim is to evaluate whether serial measurement of sCD14-ST after suspected sepsis onset is of additive predictive value for the…
The aim of this study is to characterize the composition of amniotic fluid, collected during preterm delivery, of extremely preterm infants (24-28 weeks), using novel molecular techniques. These approaches include microbial (e.g. IS-pro analysis)…
To investigate the effect of implementing continuous antepartum eCTG monitoring at the OHC, on perinatal and maternal outcomes and obstetric care
We will assess the (cost-)effectiveness of implementing two interventions in the birth centre setting:1. TcB measurement as a non-invasive screening tool to identify jaundice.2. Application of phototherapy in the birth centre.We hypothesise that…
To obtain a fundamental understanding if and which chemotherapeutic agents used for treating cancer during pregnancy are associated with offspring (epi)genetic changes, potentially causing FGR and childhood/adult diseases later in life.
Comparison of prenatal and postnatal cardiac function assessed by echocardiography using 2-D, 3-D, pulsed wave Doppler, Tissue Doppler and (blood) speckle tracking (focussing on strain and strain rate) between fetuses/neonates with structural heart…
Primary ObjectiveIn order to assess the effects of anti TNFα on the development of adaptive and innate immunity, children exposed to anti TNFα (with or without other immunosuppressive drugs) will be compared to children exposed to immunosuppressive…
Our primary objectives are: 1. To evaluate the effect of Family Integrated Care in SFR on neurodevelopmental outcome at 2 years of (corrected) age in newborns hospitalized in a level-2 Neonatal Ward for at least 1 week as compared to standard…
To study cognitive and behavioral outcome and resting-state dynamics in children with a history of perinatal asphyxia before and after the introduction of hyothermia and to compare these data with a group of controls.
Primary objective: to determine the association between social and cognitive performance of preterm-born young adults and their early motor repertoire up to 3 months after term. Secondary objective: to describe the social and cognitive functioning…