22 results
The purpose of this study is to evaluate whether thyroid hormone replacement therapy in type 2 diabetic patients suffering from overt hypothyroidism will improve muscular mitochondrial function, lower ectopic fat accumulation in muscle and liver,…
Primary Objective: 1) To study impairment and developmental delay in social cognition (and related cognitive functions) caused by brain damage in patients treated for a brain tumour in childhood as compared to a reference group of chronically ill…
The proposed phase II study will test the hypothesis that preventive swallowing exercises (PSE) during treatment will reduce the incidence of swallowing dysfunction among patients with HNSCC treated with curatively intended (CH)-RT using SWIMRT. As…
To evaluate the effect of chemotherapy on the serological and cellular immune response to influenza virus vaccination in patients with breast or colorectal cancer in order to establisch the optimal timing of vaccination during treatment with…
The primary aim of this study is to investigate the effect of imitation of a role model and the effect of convivial eating on the intake of a vegetable in children aged 4 to 6 years of age.The aim in a more long-term perspective is to develop…
The present study aims at comparing the post-operative lung injury of a lung*protective mechanical ventilation strategy (with the use of higher levels of PEEP and intra*operative recruitment maneuvers) with conventional mechanical ventilation (lower…
The primary objective is to measure the real-world daily activity in a representative cohort of 1100 longterm survivors after Ewing tumor treatment using portable devices, and to describe the functional outcome and health-related quality of life…
Main objective This research focuses on the outcomes of domestic violence at various levels in the family system, where we consider the severity of domestic violence as a determining factor. The relationships in the model are tested in families…
To find out if there is a protective effect of postconditioning on ischemia reperfusion-injury in kidneytransplantation.
PrimaryTo assess the efficacy of scalp cooling in preventing allopecia due to Myocet chemotherapy by the objective method of trichometry. Secondary:* Assess the efficacy of scalp cooling by comparing the objective method (trichometry) with the…
Primary objective:Determine the incidence rate of inhibitor formation in PUPs with severe and moderately severe hemophilia A during the first 50 exposure days (EDs) to starting with a once weekly prophylactic regimen together with the minimization…
1) To investigate the impact of keeping/loosing diabetes on quality of life and psychological well-being in a group of (morbidly) obese patients who underwent bariatric surgery, and 2) To explore whether we can predict postoperative quality of life…
The main objective of this study is to determine if the SPC has added benefits in optimising risk factors to prevent recurrent stroke, as compared with secondary prevention performed by the GP.
Is the radiological, histological and biomechanical condition of bone altered after long term bisphosphonate treatment in bone that is subjected to either compressive of distractive forces.
Confirm an association between RA and periodontitis and unravel pathogenic mechanisms underlying this association.
The primary purpose of this study is to determine the relation between a physically active lifestyle and the primary and secondary prevention of diseases and death.Using an online questionnaire, we will approach all civilian participants of the…
This study will answer the question if (repeated) abdominal amnioninfusion after midtrimester PPROM with associated oligohydramnios improves perinatal survival and prevents pulmonary hypoplasia and other neonatal morbidities. Moreover, it will…
The primary objective of the study is to relate depression and anxiety in CHF patients receiving an ICD to the occurrence of ventricular tachyarrhythmias. Secondary objectives of the study are:Assessment of the effects of depression and anxiety on…
The aim of the study is to evaluate the effectiveness of FRIENDS for Life as an indicated school-based prevention programme for children with early or mild signs of anxiety or depression.
Link inter-individual differences in light sensitivity (measured by melatonin suppression) to molecular pathways in primary fibroblasts in SAD patients and healthy controls and with light therapy succes in SAD patients and with gene variation in two…