259 results
The main aim of this research is to search for sensitive and specific QEEG markers to differentiate between children with a developmental disorder, in this case ADHD and ASD, and a control group and to differentiate between these two developmental…
The overall aim of the study is to improve diagnostic and therapeutic options for people with CF, especially in the context of young children and novel CFTR-targeting drugs. Primary Objective: 1. to demonstrate relations between CFTR genotype,…
1) Evaluating the effect and recovery of glioma surgery in eloquent areas on cognitive functioning.2) Examining the effec tof glioma surgery in eloquent areas on quality of life.3) Examining the effect of gliomas in eloquent areas on the…
- To determine whether there is a mitigated immediate immune response to islet infusion in immunosuppressed recipients- To determine if complement activation during immediate immune response is affected in immunocompromised recipients
Primary objective of this study is to assess the reliability and validity of the neuromuscular parameters of ankle joint impedance estimated by nonlinear SIPE technology in children with CP compared to current clinical manual tests and gait analysis…
Primary Objective: To assess whether both OCT (optical coherence tomography) and/or HSI (hyperspectral imaging) detect differences in glioma tissue as compared to healthy tissue as examined during brain-surgery.Secondary Objective(s): To assess if…
To investigate whether enhanced expression of growth factor receptors (FGF-R, PDGF-R and VEGF-R) and increasedvascular cell proliferation in the lung of IPF or PAH patients can be assessed using [11C]-Nintedanib or [18F]-FLTPET/CT imaging.
Considering the lack of consensus, we feel these mechanisms merit additional focus and research. LD transfer changes shoulder anatomy and thus affects the complex interplay in the glenohumeral and scapulothoracic joints. So far, no study has been…
In the proposed project we aim to predict falls in daily life and to identify both aging- and disease-related impairments that underlie impaired postural control and an increased risk of falling in daily life.
Analysis of volatile organic compounds in exhaled air as a non-invasive biomarker for liver diseases
To identify VOC profiles in exhaled air that are unique for specific liver diseases.
To determine metabolites and natural occurring peptides in urine by mass spectrometry in patients with hepatocellular carcinoma. This study is designed as a validation study; in a smaller study a spectrum of metabolites and natural occurring…
The aim of the study is to answer the following questions:On which measures do patients with aphasia seem to differ from controls matched on age and country of origin, in the analysis of the spontaneous speech according to the guidelines of the ASTA…
Aims: 1. To optimize the diagnosis of M. pneumoniae infections by discriminating between colonization and symptomatic infection using quantitative PCR. 2. To study the role of host factors (age, and bacterial and viral co-infection) on infection by…
The goal of this project is, in co-operation with the TU-delft, to develop a new diagnostic tool to discriminate dystonic muscles from healthy muscles contracting compensatory. This would enable us in the future to identify dystonic muscles more…
1) To demonstrate an elevated troponin concentration before exercise and a rise of troponin after exercise in both pre-clinical HCM mutation carriers and HCM patients with the hypertrophic phenotype, 2) To evaluate the troponin rise in relation to…
Primary Objective: To relate the ability to react in time to postural perturbations to set-shifting performance in Parkinson*s disease patients.Secondary Objective: To investigate the difference in set-shifting stepping responses between PD and…
The objective is to describe the nature and underlying (neuromuscular en biomechanical) factors of dysphagia in different neuromuscular diseases in relation to different consistencies of food. Identifying the contributing factors are starting points…
To demonstrate that CLT is more sensitive for keratoconus detection compared to other corneal topography methods.
The aim of this study is to compare the 16S PCR technique with standard bacterial cultures of infected vascular grafts, mycotic aneurysms and non-infected aortic aneurysms.
To investigate whether it is possible to induce epileptiform activity with TMS. We expect to see abnormal discharges on TMS-EEG and we expect that these findings are of diagnostic value and will help to localize the epilepsy.