92 results
This study has been transitioned to CTIS with ID 2024-518966-28-00 check the CTIS register for the current data. The primary goal of this study is to investigate the effects of belimumab on the composition of lymph nodes and the inflamed synovial…
The objectives of this study are: 1. to identify new genetic variants causing or predisposing to PD; 2. to characterize the clinical phenotype in PD associated to specific genetic variants; 3. to investigate the molecular mechanisms of PD in…
We aim to describe and identify distinct daily glucose patters (DGP) in the general population that are related to increased risk of diabetes and diabetes related micro- and macro-vascular complications using the flash sensor technology through the…
The main objective of this study is to assess patient reported outcome measures of adult patients who are diagnosed with a distal radius fracture and treated with a patient-specific 3D- printed splints as compared to a control cohort.
The primary objective of this Clinical Investigation is to evaluate the diagnostic yield using the Ion Endoluminal System when used with adjunctive 3D imaging modalities for the biopsy of peripheral pulmonary nodules (PPNs). In a first phase, the…
Investigation of pelvic blood circulation by MRI in women with a gynaecological cancer who will have curative radiotherapy with or without weekly HT for inoperable pelvic tumours.
In this clinical pilot study we want to gather data in order to calculate a power for correct subject group to answer the following research question: to explore the relation between NETs/cfDNA in the blood and NETosis in burn wounds and their…
To identify molecular biomarker profiles that are associated with cervical tumorigenesis, and that can be used for development of an algorithm for detection of low grade CIN1, CIN2, CIN3 and cervical cancer. The algorithm should provide advice for a…
To determine the feasibility (main aim) and effectiveness (secondary aim) of a prehabilitation program in patients with HNC or liver cancer
Primary objective is to investigate the effect of VR on patient-reported pain outcomes in the ED. Secondary objectives are to investigate the effect of VR on analgesics use, patient-reported outcomes, and process indicators and to identify barriers…
The primary objective is to explore the urine microbiome (urobiome) composition of postmenopausal women with and without RUTI at five scheduled time points during one year of follow-up, as well as before, during, and after UTI episodes when they…
The primary objective of this study is to assess wall shear stress in the left ventricle outflow tract using 4D flow CMR in healthy controls, asymptomatic HCM and before and after surgical myectomy in patients with HOCM,
Our primary objective of the feasibility study is to assess the acceptability and feasibility of the developed 2EAT dietary treatment in older adults with obesity. The primary objective the main study (RCT) is to investigate whether a shift towards…
Primary Objectives- To evaluate disease-related characteristics and biomarkers in patients with CLE compared to healthy volunteers. Secondary Objectives- To evaluate the variability of the selected biomarkers between patients - To investigate the…
Our study uses a two-step approach. In the first step (study part 1), we will assess the feasibility of the ADJUST-AFO to measure the optimization parameter, walking energy cost, while changing the stiffness during 20 minutes walking in healthy…
In this study, we therefore aim to investigate how trained immunity is systemically regulated in ANCA vasculitis patients and how the degree of trained immunity affects disease activity and severity. A better understanding of these processes…
The aim is to investigate changes in nocturnal and postprandial glucose and glycogen metabolism in individuals with IFG and IGT when compared to healthy, non-diabetic, overweight participants. In addition, it will be investigated if reducing…
The aim of this study is to investigate the effectiveness of MST-ID for adolescents with severe behavioural problems from families with an intellectual disability (ID), compared to standard MST. It is hypothesised that MST-ID (n = 150 families) is…
The objective of this study is to evaluate the gastro-intestinal tolerance, nutritional intake, and acceptability of an adjusted composition of an enteral tube feed for adults in need of long term nutritional support.
The objective of the study is to investigate the feasibilty, acceptabilty, implementation and preliminary (cost-)effectiveness of the intervention on recovery, health and lifestyle variables.