75 results
Primary objective: To determine the characteristics of language, speech and motor functions in MCI due to AD, mild AD and moderate AD Secondary objective: To explore the association between language, speech and motor functions in MCI due to AD and…
The primary aims of this study are therefore to 1) compare DmO2 derived via NIRS between young sedentary, young endurance-trained, older sedentary, and older endurance-trained subjects; 2) to compare non-invasive (i.e. with NIRS and 31phosphorous…
To investigate whether implementation of a best practice program for preoperative optimisation of patients with a focus on screening, assessment, and intervention of 8 potentially (partly) modifiable risk factors (low (aerobic) fitness level,…
To assess the effects of anesthetics on local (cerebral) microvascular parameters in craniotomy patients. Secondary objective: To assess the effects of anesthetics on systemic (sublingual) microvascular parameters in craniotomy patients.
The aim of this observational and exploratory study is to describe the accuracy of gaze stabilization in the presence of abnormal vestibular and visual functions. Visually induced image movements are used as the basis for gaze stability for each…
Main objective is to determine whether nerve excitability can detect drug-induced effects of Riluzole in yet treatment- naïve patients with ALS. Secondary objectives are to determine the correlation between the Riluzole plasma concentration levels…
The aims of this project are to 1) to determine the non-inferiority of inter-CBT, compared to a benchmark study where CBT was provided by psychologists (TIRED study), in its effect on reduction in cancer-related fatigue, 2) to adapt CBT delivery to…
To compare the effects of three different protein-enhancement strategies (whey protein (WP), mixed plant-based protein (BRFP), and use of protein-rich food products (PFP) on exercise-induced muscle damage in older adults compared to isocaloric…
The primary objective of this study in people with PD is to examine the clinical feasibility, in terms of safety, adherence, performance and user experience (i.e., patient and physiotherapist), and effectiveness of home-based gamified cueing-…
The primary objective of this study is to demonstrate that the EnzySystem HemA version A can record TG and quantify FVIII activity levels within a time frame of 60 min in fresh whole blood samples of healthy volunteers and patients with hemophilia A…
Objective: Identification of host biomarker signatures that have discriminatory difference in patients with a bacterial respiratory tract infection. Secondary objectives Identification of host biomarker signatures that have discriminatory difference…
To assess the inflammatory secretome of EAT, its subsequent interaction with cardiomyocytes, and its potential implication in the development of LV diastolic dysfunction.
A future project will focus on a new platform for at-home monitoring and testing of cochlear implants, developed by one of the manufacturers of cochlear implants, Advanced Bionics (AB). Their Research Application allows for clinicians to read out…
To improve aftercare for patients with ABI receiving outpatient rehabilitation, aimed at promoting an active lifestyle to prevent persistent complaints after ABI and poor HR-QoL.
Primary objective:To investigate the treatment success using the GCSI-score in patients with refractory GP undergoing G-POEM compared to patients receiving a PEG-J at t = 6 months.Secondary objectives:1. To investigate the treatment success using…
Primary Objective: to investigate the prevalence of bruxism and TMD in PD patients through objective measurements.Secondary Objectives: to identify factors associated with the presence of TMD or bruxism in a PD population.
Our aim is to identify cognitive dysfunction in patients with a cerebellar pontine angle tumour (koos classification grade 4 schwannoma) that have been operated in order to prevent cognitive decline in future patients. For this purpose, we want to…
Primary objective:1) To determine the discriminating ability of the microvasculature between uteri with adenomyosis, myomas and no uterine disorders. Secondary Objectives: 2) To determine the discriminating ability of the microvasculature between…
The overall aim is to investigate whether a coach-supported mHealth intervention for lifestyle improvement can reduce the risk of dementia in those with low SES and/or a migration background aged 50-75 years. The specific objectives are to…
The aim of this project is therefore to measure the effect of the neuro visual rehabilitation and to (re)organize the care from Visio based on the client's request for help and condition.