2094 results
The primary objective is to identify clinical and biological measures that discriminate paediatric ME/CFS and post-COVID patients from healthy controls based on either clinical (based on physiological tests and questionnaires) and biological (based…
Upregulation of the inflammatory response in skin of patients with atopic dermatitis, psoriasis or cutaneous LE coincides with the expression and secretion of a distinct set of proinflammatory markers, including cytokines, chemokines and soluble…
The INFINITE trail aims to successfully implement ICG-fluorescence for identifying the SLN by: 1) guiding the implementation process using the Effective Implementation of Change model developed by Grol and Wensing; 2) identifying and understanding…
The general aim of this project is to determine the (cost-)effectiveness of footwear modification in addition to GP-led usual care, compared to GP-led usual care alone for patients with first MTP joint osteoarthritis (OA) at 6 months of follow-up…
The primary goal of this study is to identify immunological alterations in blood, lymphoid tissue, bone marrow and muscle in IIM patients. Furthermore, our objective is to specifically profile autoreactive B lineage cells from IIM patients isolated…
Our primary objective is to compare neuroimaging markers on a 3T MRI-scan with the MRI-scans that were performed during TRACK-HD in 2008-2011. We will assess the following neuroimaging markers, starting with the most important marker: 1. Structural…
Primary Objective: Assess the effect of mental imagery with fMRI-neurofeedback-based upregulation of the putamen on motor symptoms of PD Secondary Objective(s): -Assess changes in whole brain activation patterns over the course of the NF training…
Primary objective: To longitudinally characterize alterations in electrophysiological biomarkers in ALS of peripheral excitability in relation to neurodegeneration. Secundary objectives:1. To determine the value of multi-muscle CMAP-scan outcomes as…
The objective is to assess whether individuals identified with elevated Lp(a) through familial cascade screening have an increased presence of coronary atherosclerotic plaque compared to matched controls with normal Lp(a).
To assess the transcriptional, epigenetic and functional reprogramming of circulating and tissue (BM and spleen) monocytes and myeloid progenitor cells in the context of ovarian cancer.
The main objective is to explore whether digital features of dysarthria, dysphonia, proximal arm fatigue and ptosis can differentiate between participants with and without MG.
To evaluate the efficacy of a new tumor-agnostic ctDNA assay, the ctDNA estimator, to detect newly developing tumors in Lynch carriers.
The purpose of this study is to investigate the feasibility of introducing a new practice in the Emergency Department for patients who may be problematic users of prescription opioids. This involves using a questionnaire, a short motivational…
Primary To evaluate the prevalence of specific immune cell subsets in a range of IMID dermatologic disease patients, both between diseases and compared to healthy volunteers Secondary To evaluate the variability in specific immune cell…